Concussions Flashcards
Cell Death: Necrosis (Cytolysis)
Cells rupture, spilling their contents into the extracellular space
Inflammatory Response
Cell Death: Apoptosis (Programmed Cell Death)
Cells are dismantled into membrane-bound vesicles
No Inflammatory Response
Acquired Brain Injury (ABI)
Any brain injury that occurs after birth
Not hereditary, congenital, or degenerative
Causes:
Lack of oxygen
Drug toxicity
Poisoning
Traumatic Brain Injury
A sub-category of ABI
Includes only damage to the brain caused by an external mechanical force
Major cause of death and disability (#1 in children and youth)
Causes:
Concussion
Blast injury
Penetrating trauma
Physical Symptoms of TBI
Headache, Dizziness Sleep Disturbances Blurred vision/Tinnitus/Slurred speech Loss of consciousness Nausea or vomiting Balance and coordination issues Decreased reaction time
Cognitive Symptoms of TBI
Confusion Behavior/Mood changes Restlessness Agitation Memory problems Problems with concentration/attention Difficulty problem-solving
TBI Spectrum
Minimal - Mild - Moderate - Severe
Dependent on symptoms, injury, and force
Mechanics of TBI
When a blow is sufficiently forceful CSF is unable to protect the brain within the skull resulting in a collision between the brain and skull
Three Steps in TBI
- Site where brain and skull first make contact (COUP)
- Pressure cause brain to rebound and contact skull on opposite side (CONTRE-COUP)
- This motion continues until the energy dissipates