Compulsion and Dependence Disorders Flashcards

1
Q

what is OCD?

A

recurrent obsessional thoughts and compulsive acts

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2
Q

what are compulsive acts?

A

repeated rituals or stereotyped behaviour, non enjoyable and functional

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3
Q

what are obsessional thoughts?

A

ideas/images/impulses enter mind in a stereotypes way, unpleasant and resisted

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4
Q

tx of OCD?

A

CBT
tricyclic - clomipramine
SSRI

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5
Q

what are the 3 risk categories for alcohol misuse?

A

high risk >35 a week
increased 15-35 a week
low 14 a week, spread over 3 days

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6
Q

features of alcohol/drug dependence?

A
desire/compelled to take drug
withdrawal state
tolerance
neglect of other pleasures
use despite evidence of harmful consequences
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7
Q

Ix for alcohol dependence?

A

LFTs (GGT)
MCV
carbohydrate deficient transferrin (MEN)

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8
Q

questionnaires for alcohol dependence?

A

FAST

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9
Q

features of wernicke’s encephalopathy?

A

ataxia
opthalmoplegia
nystagmus
reduced consciousness

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10
Q

Tx for alcohol detoxification?

A

benzodiazepines
thiamine (to prevent WE)
analgesia
antiemetics

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11
Q

what is used for alcohol relapse prevention?

A

naltrexone

diulfirman

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12
Q

when does alcohol withdrawal state most commonly occur?

A

24-28hrs from last drink

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13
Q

featurs of alcohol withdrawal state?

A
tremor
sweaty
anxiety
N+V
insomia
tachycardia
seizures
systolic HT
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14
Q

when does alcohol withdrawal state resolve?

A

5-7days

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15
Q

what is delirium tremens?

A

rapid onset of confusion caused by alcohol withdrawal

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16
Q

when does delirium tremens occur?

A

after 2 days of abstinence

17
Q

features of delirium tremens?

A
insidious onset night time confusion 
fever
paranoid
hallucinations
disorientated
18
Q

why does korsakoff syndrome occur?

A

hypothalamic damage and cerebral atrophy due to thiamine deficiency

19
Q

features of korsakoff syndrome?

A

loss of anterograde memory
lack of insight
lack of apathy

20
Q

what is used as an opiate substitute?

A

methadone or buponephrine

21
Q

how to calculate units of alcohol?

A

(% x volume) /10

22
Q

Tx for opiate overdose?

A

naloxone

23
Q

what does alcohol withdrawal cause in the brain?

A

excess glutamate

reduced GABA

24
Q

what is given to alcoholics to protect against wernicke’s encephalopathy?

A

thiamine

25
Q

what causes wernicke’s encephalopathy?

A

B1 (thiamine) deficiency