Compression Neuropathy Flashcards
Definition of compression neuropathy?
process why a nerve becomes entrapped and it passes through a narrowing (tunnel, passage, etc). Can happen anywhere along length of a nerve
Biomechanical causes of CN
space occupying lesions, degenerative causes, post-trauma, mechanical/movement, spondylolisthesis
ex of space occupying lesions
herniated discs, cysts
ex of degenerative cause of CN
foraminal stenosis
ex of post-trauma cause of CN
fracture, hematoma, compression from equipment
ex of mechanical/movement cause of CN
muscle spasm, pinching from external or positional forces
Systemic causes of CN
pregnancy, hypothyroidism, diabetes
Anatomy of a nerve from inside out
axons covered by myelin sheath covered by endoneurium > grouped together in fascicles and covered by perineurium > groups of fascicles and the vessels and CT are surrounded by epineurium
microscopic pathological changes (of the nerve) that can be seen in CN
microvascular compressions (leading to ischemia), thickening of epineurium, thinning of myeline sheath, microtubular closure, axonal degeneration
What category of nerve injury is Neuropraxia? and what is it?
Neuropraxia = 1st degree injury.
involves focal damage of myelin fibers around the axon, but the CT sheath remains intact
Recovery: limited course from days to weeks (lease severe)
What category of nerve injury is axonotmesis and what is it?
Axonotmesis = 2nd degree injury.
There is some disruption/injury to the AXON itself, MYELIN SHEATH remains INTACT.
Recover: REGENERATION is possible, but PROLONGED (takes months) without a complete recovery
What category of nerve injury is neurotmesis?
Neurotmesis: can be a 3rd or 4th or 5th degree nerve injury
What would a 3rd degree nerve injury look like?
Neurotmesis
-disruption of the axon AND the endoneurium
Recovery: No axonal regeneration because there is INTRANEURAL FIBROSIS
What would a 4th degree nerve injury look like?
Neurotmesis
-disruption of the AXON and ENDONEURIUM and PERINERIUM (aka nerve fasciculi). There will be a large area of INTRANEURAL SCARRING at site of injury = prevents axon from advancing distal to the level of injury.
Recovery: if be NO IMPROVEMENT in function…need SURGERY to restore
What would a 5th degree nerve injury look like?
Neurotmesis
-disruption of the AXON and ENDONEURIUM and PERINEURIUM and EPINEURIUM. There will be substantial perineural HEMORRHAGE and SCARING.
Recovery: surgery is required
Name of the system that classifies nerve injury
Sunderland Classification (1st degree - 5th degree)
What can you use to identify where/what nerve is pinched?
used dermatomes/sensation, motor, and reflex nerve roots to narrow it down
If you impinge nerve root C5 where will you see changes (motor, sensation, reflex)?
Motor: deltoid, biceps
Sense: lateral arm
Reflex: biceps
If you impinge nerve root C6 where will you see changes (motor, sensation, reflex)?
M: wrist extension, elbow flex
S: radial forearm, thrum and index finger
R: brachioradialis
If you impinge nerve root C7 where will you see changes (motor, sensation, reflex)?
M: wrist flex, elbow extension, finger extension
S: middle finger
R: triceps
If you impinge nerve root C8 where will you see changes (motor, sensation)?
M: finger flexion
S: ulnar forearm, pinky finger
If you impinge nerve root T1 where will you see changes (motor, sensation)?
M: finger abduction
S: medial arm
Most common cause of cervical nerve root compression?
usually a secondary manifestation of cervical disc disease (bulging disc or disc herniation)
What type of damage will you see in bulging disc
disc is compressed evenly without significant damage to the cartilage rings
What type of damage will you see in herniated disc
Protrusion: only a few cartilage rings are torn and there is no leakage of central material
Extrusion: cartilage rings have torn in a small area and the nucleus pulposus is able to flow out of the disc space
most common direction of disc rupture and complication
posterior-lateral –> compresses nerve root as it exists intervertebral foramen = radiculopathy
general treatment progression for CN:
first try conservative measures (splinting/NSAIDS/injections?OMM/PT for 3-6mon*)»_space; if non-operative management fails consider surgical release
*exception is cubital tunnel syndrome
How does the treatment of cubital tunnel syndrome differ from the rest of the CN treatments?
surgical release is considered/justified in almost all cases (except the most mild) to prevent nerve damage
What nerves are at risk for UE CN?
radial N
median N
ulnar N
musculocutaneous and axillary Ns
What does the radial nerve do (motor, sensation)?
M: triceps, anconeus, wrist extensors
S: most of dorsum of the hand (via posterior interosseous N)
What are the 3 sites for radial nerve entrapment?
1) high on the humerus
2) Radial tunnel
3) at the wrist
High on the humerus radial n entrapment: cause/symptoms
cause: usually 2ndary to humerus fx or compression near spiral groove.
Pt will have WRIST DROP, WEAK ELBOW FLEX, +/- diminished tricep reflex, paresthesia.
Function should return in 4-5mon
Radial tunnel radial n entrapment: causes/symptoms
causes: repetitive rotatory movements (rowing, discus, tennis), heavy manual labor
Pt will have pain and tenderness 5cm distal to lateral epicondyle with wrist drop or pain + restricted to supination
radial nerve entrapment at the wrist: causes/symptoms
causes: the superficial/sensory branch is pinched during pronation
pt will have sensation changes over posterolateral hand (back of hand near thumb, digit 1 and digit 2)
What are the 3 other names for “handcuff neuropathy”? and what are the symptoms?
compression of superficial radial n
cheiralgia paresthetica
wartenberg’s syndrome
symptoms: numbness/tingling/burning/pain in SRN distribution (back of hand)
What are the 4 sites of median nerve entrapment?
- ligament of struthers (somewhere near the elbow)
- bw the superficial and deep heads of the pronator teres m = pronator syndrome
- distal to the pronator teres deep = AIS
- under the flexor retinaculum = carpal tunnel