Compression Neuropathy Flashcards

1
Q

Definition of compression neuropathy?

A

process why a nerve becomes entrapped and it passes through a narrowing (tunnel, passage, etc). Can happen anywhere along length of a nerve

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2
Q

Biomechanical causes of CN

A

space occupying lesions, degenerative causes, post-trauma, mechanical/movement, spondylolisthesis

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3
Q

ex of space occupying lesions

A

herniated discs, cysts

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4
Q

ex of degenerative cause of CN

A

foraminal stenosis

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5
Q

ex of post-trauma cause of CN

A

fracture, hematoma, compression from equipment

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6
Q

ex of mechanical/movement cause of CN

A

muscle spasm, pinching from external or positional forces

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7
Q

Systemic causes of CN

A

pregnancy, hypothyroidism, diabetes

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8
Q

Anatomy of a nerve from inside out

A

axons covered by myelin sheath covered by endoneurium > grouped together in fascicles and covered by perineurium > groups of fascicles and the vessels and CT are surrounded by epineurium

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9
Q

microscopic pathological changes (of the nerve) that can be seen in CN

A

microvascular compressions (leading to ischemia), thickening of epineurium, thinning of myeline sheath, microtubular closure, axonal degeneration

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10
Q

What category of nerve injury is Neuropraxia? and what is it?

A

Neuropraxia = 1st degree injury.
involves focal damage of myelin fibers around the axon, but the CT sheath remains intact
Recovery: limited course from days to weeks (lease severe)

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11
Q

What category of nerve injury is axonotmesis and what is it?

A

Axonotmesis = 2nd degree injury.
There is some disruption/injury to the AXON itself, MYELIN SHEATH remains INTACT.
Recover: REGENERATION is possible, but PROLONGED (takes months) without a complete recovery

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12
Q

What category of nerve injury is neurotmesis?

A

Neurotmesis: can be a 3rd or 4th or 5th degree nerve injury

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13
Q

What would a 3rd degree nerve injury look like?

A

Neurotmesis
-disruption of the axon AND the endoneurium
Recovery: No axonal regeneration because there is INTRANEURAL FIBROSIS

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14
Q

What would a 4th degree nerve injury look like?

A

Neurotmesis
-disruption of the AXON and ENDONEURIUM and PERINERIUM (aka nerve fasciculi). There will be a large area of INTRANEURAL SCARRING at site of injury = prevents axon from advancing distal to the level of injury.
Recovery: if be NO IMPROVEMENT in function…need SURGERY to restore

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15
Q

What would a 5th degree nerve injury look like?

A

Neurotmesis
-disruption of the AXON and ENDONEURIUM and PERINEURIUM and EPINEURIUM. There will be substantial perineural HEMORRHAGE and SCARING.
Recovery: surgery is required

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16
Q

Name of the system that classifies nerve injury

A

Sunderland Classification (1st degree - 5th degree)

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17
Q

What can you use to identify where/what nerve is pinched?

A

used dermatomes/sensation, motor, and reflex nerve roots to narrow it down

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18
Q

If you impinge nerve root C5 where will you see changes (motor, sensation, reflex)?

A

Motor: deltoid, biceps
Sense: lateral arm
Reflex: biceps

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19
Q

If you impinge nerve root C6 where will you see changes (motor, sensation, reflex)?

A

M: wrist extension, elbow flex
S: radial forearm, thrum and index finger
R: brachioradialis

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20
Q

If you impinge nerve root C7 where will you see changes (motor, sensation, reflex)?

A

M: wrist flex, elbow extension, finger extension
S: middle finger
R: triceps

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21
Q

If you impinge nerve root C8 where will you see changes (motor, sensation)?

A

M: finger flexion
S: ulnar forearm, pinky finger

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22
Q

If you impinge nerve root T1 where will you see changes (motor, sensation)?

A

M: finger abduction
S: medial arm

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23
Q

Most common cause of cervical nerve root compression?

A

usually a secondary manifestation of cervical disc disease (bulging disc or disc herniation)

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24
Q

What type of damage will you see in bulging disc

A

disc is compressed evenly without significant damage to the cartilage rings

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25
Q

What type of damage will you see in herniated disc

A

Protrusion: only a few cartilage rings are torn and there is no leakage of central material
Extrusion: cartilage rings have torn in a small area and the nucleus pulposus is able to flow out of the disc space

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26
Q

most common direction of disc rupture and complication

A

posterior-lateral –> compresses nerve root as it exists intervertebral foramen = radiculopathy

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27
Q

general treatment progression for CN:

A

first try conservative measures (splinting/NSAIDS/injections?OMM/PT for 3-6mon*)&raquo_space; if non-operative management fails consider surgical release
*exception is cubital tunnel syndrome

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28
Q

How does the treatment of cubital tunnel syndrome differ from the rest of the CN treatments?

A

surgical release is considered/justified in almost all cases (except the most mild) to prevent nerve damage

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29
Q

What nerves are at risk for UE CN?

A

radial N
median N
ulnar N
musculocutaneous and axillary Ns

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30
Q

What does the radial nerve do (motor, sensation)?

A

M: triceps, anconeus, wrist extensors
S: most of dorsum of the hand (via posterior interosseous N)

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31
Q

What are the 3 sites for radial nerve entrapment?

A

1) high on the humerus
2) Radial tunnel
3) at the wrist

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32
Q

High on the humerus radial n entrapment: cause/symptoms

A

cause: usually 2ndary to humerus fx or compression near spiral groove.
Pt will have WRIST DROP, WEAK ELBOW FLEX, +/- diminished tricep reflex, paresthesia.
Function should return in 4-5mon

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33
Q

Radial tunnel radial n entrapment: causes/symptoms

A

causes: repetitive rotatory movements (rowing, discus, tennis), heavy manual labor
Pt will have pain and tenderness 5cm distal to lateral epicondyle with wrist drop or pain + restricted to supination

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34
Q

radial nerve entrapment at the wrist: causes/symptoms

A

causes: the superficial/sensory branch is pinched during pronation
pt will have sensation changes over posterolateral hand (back of hand near thumb, digit 1 and digit 2)

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35
Q

What are the 3 other names for “handcuff neuropathy”? and what are the symptoms?

A

compression of superficial radial n
cheiralgia paresthetica
wartenberg’s syndrome

symptoms: numbness/tingling/burning/pain in SRN distribution (back of hand)

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36
Q

What are the 4 sites of median nerve entrapment?

A
  1. ligament of struthers (somewhere near the elbow)
  2. bw the superficial and deep heads of the pronator teres m = pronator syndrome
  3. distal to the pronator teres deep = AIS
  4. under the flexor retinaculum = carpal tunnel
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37
Q

What is the most common compression syndrome?

A

Carpal tunnel syndrome (median n entrap)

38
Q

What are the functions of the median N (motor).

A

forearm flex and pronation, wrist flex and radial deviation, thumb abduction and opposition, index/middle finger abduction and flexion

39
Q

What three syndromes did we discuss that are due to median N entrapment?

A

Pronator syndrome
Anterior Osseous Syndrome
Carpal Tunnel Syndrome

40
Q

Pronator syndrome: cause,S&S, dx tests

A

MEDIAN N
cause: repetitive pronating motions = piano, fiddlers, baseball, dentists, lifting weights
S&S: achy pain in mid/prox forearm that is worse with repeated lifting. +/- sensory changes in radial 3.5 fingers
Dx: pt will have pain with resisted forearm pronation

41
Q

Anterior Interosseous Syndrome (AIS): causes, S&S, dx tests, treatments

A

MEDIAN N
causes: trauma (cast pressure), bulky tendon of pronator teres m, soft tissue masses, fibrous bands
S&S: NO SENSORY SYMPTOMS (bc deep motor branch of median N) = flexor weakness
dx tests: “OK” sign can’t make round “O”, the fingers pinch flat
Tx: splint elbow in 90deg of flex for 12wks max

42
Q

Carpal Tunnel Syn: causes, S&S, dx test

A

MEDIAN N
causes: repetitive motion jobs with wrist flexion common, pregnancy
S&S: nighttime numbness of lateral 3.5fingers, tingling, wrist pain, you drop shit, thenar atrophy
Dx: EMG is gold-standard (but it hurts?). Phalen’s test. Tinel’s test. 2-pt discrimination (can’t tell if closer than 5mm).

43
Q

Treatment methods for Carpal Tunnel?

A

NSAIDS… steroid injections/surgery if everything else doesn’t work
OMT: MFR, ST, lymphatics (if preggers)
xray (if think fx), MRI (if soft tissue injury)
stop repetitive motions, splint wrist at 30deg extension @night

44
Q

Two locations for ulnar nerve entrapment?

A
  1. cubital tunnel = cubital tunnel syndrome

2. guyon’s canal

45
Q

Ulnar nerve: motor, sensory

A

motor: muscles of ulnar side of forearm and hand (flexors). deep branch in hand = interosseous and adductor pollicis
sense: ring finger? and pinky

46
Q

What is the name of the syndrome we talked about in class that deals with ulnar n entrapment?

A

Cubital Tunnel Syndrome = most common compression in the elbow

47
Q

What structures form the cubital tunnel (and are therefore the cause of the compression)

A

medial epicondyle, medial trochlea, olecranon, ulnar collateral L

48
Q

What activities can cause Cubital Tunnel syndrome?

A

baseball pitchers, prolonged elbow flexion during sleep, external compression against something hard, thickened cubital tunnel retinaculum.

49
Q

Cubital Tunnel syndrome: S&S, dx tests, tx?

A

S&S: paresthesia to 4th and 5th digits, medial elbow pain that radiates to the hand with decreased intrinsic muscle strength = can’t turn key in a door
dx tests: (+) Tinel’s test at elbow, Froment’s sign (pinch paper)
symptom reproduction with elbow flex and wrist ext
tx: general and padded elbow sleeve to limit terminal elbow flexion + cushions

50
Q

What things are compressed in thoracic outlet syndrome?

A

brachial plexus and/or subclavian vessels

51
Q

What are the 3 sites of compression in thoracic outlet syn (TOS)?

A
  1. scalene triangle (bw the anterior and middle scalenes)
  2. costoclavicular passage (under the clavicle)
  3. pec minor attachment at coracoid process
52
Q

What are the symptoms of TOS?

A

weakness, paresthesia of medial arm, forearm, and hand that is made worse with overhead activities

53
Q

If you suspect TOS take these steps for diagnosis…

A
  1. c-spine xray if yes = cool. if unclear/negative > EMG if diagnosis = cool if inconclusive > arteriography or venography
54
Q

What are the special tests and results that would indicate TOS?

A
  1. Military/costoclavicular maneuver = hold pt arms in extension and abduction, they retract scapula/ext spine. (+) with symptom reproduction/dec pulse
  2. East/Roos test = open close hands above head. (+) with symptom reproduction
  3. Wright’s hyperabduction test =
    Adson’s test = monitor radial pulses as they look away. (+) decrease in pulse on side contralat to the direction they’re looking
55
Q

A (+) Wright’s hyperabduction test indicates what?

A

thoracic outlet syndrome due to Pectoralis Minor m

56
Q

What LE nerves are at risk of compression and what are their nerve roots?

A

Common Fibular N (peroneal n) = L4-S2
Deep fibular n = L4-S2
posterior Tibial N = L4-S2
lateral fermoral cutaneous n = L2, L3

57
Q

L1 and L2: motor, sense?

A

motor: hip flex
sense: inguinal crease (L1) and anterior thigh (L2)

58
Q

L2 and L3: motor, sense?

A

motor: knee extension
sense: anterior thigh (L2) and ant thigh just above knee (L3)

59
Q

L4: motor, sense, reflex?

A

motor: ankle dorsiflexion
sense: knee, medial leg and foot
reflex: patellar

60
Q

L5: motor, sense?

A

motor: extensor hallucis longus
sense: lateral leg, dorsum of the foot

61
Q

L6: motor, sense, reflex?

A

motor: ankle plantarflexion
sense: lateral foot and plantar aspect of foot
reflex: achilles

62
Q

What nerve is compressed in meralgia paresthetica?

A

Lateral femoral cutaneous N

63
Q

What causes meralgia paresthetica?

A

lat fem cut n compression in inguinal canal

from… v hard sports, fat, tight belt, seatbelt, anatomic abnormality = runs through sratorius m

64
Q

What are the symptoms of meralgia paresthetic?

A

numbness/burning on skin of ANTEROLATERAL THIGH, eventually trophic skin changes, (+) tinne’s sign 1cm inferomedially to ASIS

65
Q

What do the branches of the common fibular N innervate?

A

the deep branch of CFN: anterior compartment of leg (tibialis anterior, extensor digitorum longus and brevis, extensor hallicus longus).
the superficial branch of CFN: lateral compartment (fibularis longus and brevis)

66
Q

What are the nerve roots associated with the common fibular N?

A

L4-S2

67
Q

what are some causes of Common fibular nerve compression?

A

compression as nerve enters fibular tunnel (lat side of knee)

  • leg hooked over a rail (bedridden, coma, post-op)
  • lots of squatting (picking stawberries)/or lotus position
  • ankle sprain/trauma to fibular head
  • lithotomy position during childbirth
  • idiopathic
68
Q

Common fibular n compression: S&S, tx?

A

s&s: pain along proximal 1/3 of lateral leg, FOOT DROP = SLAPS THE FLOOR, symps worse during plantarflex & inversion
Tx: post fibular head HVLA or ME on gastroc/soleus, biceps femoris

69
Q

What are the reason for anterior tarsal tunnel syndrome?

A

DEEP FIBULAR N compression in the tarsal tunnel at the inferior extensor retinaculum

  • trauma to distal tibia/calcaneus (ankle sprains, soccer)
  • talonavicular dysfunction
  • prolonger planter flexion
  • compression from shoes too tight
70
Q

How do you treat anterior tarsal tunnel syndrome?

A

remove compression forces, MFR of extensor retinaculum, traction tug of talonavicular joint, hiss whip navicular, cuneiforms, 1/s metatarsal

71
Q

what are symptoms of Anterior tarsal tunnel syndrome?

A

pain over dorsomedial foot that is worse at rest.

extensor digitorum brevis weakness

72
Q

Tarsal Tunnel Syndrome is caused by

A

compression of POSTERIOR TIBIAL N in the tarsal tunnel behind the medial malleolus with the overlying flexor retinaculum

73
Q

what does the posterior tibial nerve innervate: motor, sense?

A

motor to the planter muscles of the foot

sense: to plantar aspect of foot and toes

74
Q

What can cause tarsal tunnel syndrome?

A
idiopathic (50%)
space-occupying lesions
trauma to medial malleolus, distal tibia, calcaneus
ankylosing spondylitis
long time standing
75
Q

Tarsal tunnel syndrome: S&S, Tx?

A

POSTERIOR TIBIAL N
s&s: pain on planter surface of foot (vague burning/tingling/numbness), rarely effects gait
Tx: NSAIDs, US, PT, acupuncture, rest
OMM tx: MFR, HVLA

76
Q

(+) OK Sign

A

median nerve entrapment

77
Q

(+) froment’s sign

A

ulnar n entrapment

78
Q

(+) hoffman’s sign

A

CNS problem

79
Q

Stereotypical cause of median nerve entrapment syndromes:

A

pronator syndrome - weight lifter
anterior interosseous syn - post case pressure
carpal tunnel syn - gymnasts

80
Q

1 most common compression neuropathy

A

median nerve compression = carpal tunnel syndrome

81
Q

3 most common compression neuropathy

A

common fibular n compression = foot drop

82
Q

What is the path of internal herniation?

A

acute = extreme pain and then the disc slowly shrivels away in days to weeks and most resolve tx in 2-6wks. 90% back to normal activity within 1 mon

83
Q

Spinal disc disease that doesn’t resolve will have what s&s?

A

weak back ligaments that cause pain to radiate down their legs, and can accelerate osteoarthritis

84
Q

definition of radiculopathy

A

term used to describe pinching of the nerve roots as they exit the spinal cord or cross intervertebral disc

85
Q

definition of myelopathy

A

compression of the spinal cord itself

86
Q

definition of neuropathy

A

result of damage to peripheral nerves, often causes weakness, numbness and pain, usually in hands and feet

87
Q

What is sciatica?

A

A SYMPTOM. pain that comes from lower back felt along the back of the leg (not in the dermatomal pattern, but along nerve distribution).

88
Q

What is the major cause of sciatica?

A

sacroiliac ligament weakness

89
Q

What are the symptoms of sciatica?

A

pain with walking or long periods of sitting, pain when getting up from sitting. hamstrings and quadratus femoris are both tight.

90
Q

OMM Treatments of sciatica?

A

treat BOTH the hamstrings and the quadratus femoris ms so you don’t creat unbalanced tension between flexors and extensors that may make the problem worse. Release adductor magnus FIRST.