Complex Regional Pain Syndrome (CRPS) Exam 4 Flashcards

1
Q

CRPS (Complex Regional Pain Syndrome)

A

Chronic pain syndrome - must be aware b/c any dx can slip into this and not easy to treat and very painful, the sooner it is caught the better the prognosis

Previously referred to as Shoulder Hand Syndrome and Reflex Sympathetic Dystrophy - name change b/c not all pt with CRPS have sympathetic symptoms

Involves several physiological and psychological systems

Process is progressive without intervention

Impacts women 4 x more than men of which 65% are btwn the ages of 30-50

Autonomic nervous system is not under voluntary control

Problem is not just reflexive, it is very complex physiological and psychological problem, gets worse if nothing is done

Really don’t know what causes it

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2
Q

Prevalence/Risk Factors

A
* Hx of distal radius fracture - docs prescribe 500mgs of 
  Vitamin C (median nerve has a lot of autonomic fibers)
  • Identifiable peripheral nerve - type II CRPS
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3
Q

Hypertrichosis

A

Abnormal hair growth that occurs in response to an irritated cutaneous nerve

This in itself does not mean person has CRPS but lets us know that the cutaneous nerve fibers were affected - compressed in a cast

Hair will eventually fall off and go back to normal

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4
Q

Prevalence/Risk Factors

A

Children can get CRPS (usually over 5 yrs old and LE more involved)

Children under 5 and elderly rarely get CRPS

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5
Q

General Symptoms

A

Vary from person to person
* Prolonged or excessive pain out of proportion to injury
* Continuous throbbing pain
* Sensation of burning, stinging, tingling, numbness,
squeezing
* Sensitivity to heat or cold
* Swelling
* Changes in skin temp - sweaty or cold at times and
temp variance. Extremities may be either hot or cold and
there is often a diff btwn involved and uninvolved extrem
* Atrophy
Fluidotherapy is good b/c you can adjust temp to provide
desensitization

Look at temp btwn each side

S/S - skin on back of hand is shiny

S/S - starts distal and climbs up and can cross

Sometimes they can have every other sign and no pain

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6
Q

Common S/S

A
  • Inflammation
  • Skin color changes
  • Stiffness
  • Abnormal hair growth
  • Spasms in blood vessels and Mm of the extremities
  • Osteopenia - bones will lose density as it progresses
  • Insomnia/Emotional Disturbances
  • Dystonia/motor planning difficulty
Additional Symptoms:
Atrophy of hair and nails
Hypertrophy of skin
Spasms in blood vessels and Mm of the extremities
Temp variance
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7
Q

**PAIN DEFINITIONS AND TERMS

A

Hyperpathia - Abnormal painful reactions to a stimulus (umbrella term)

Diff types of hyperpathis:
Allodynia - pain in specific dermatome distribution that is a result of a stimulus that is not normally painful

Hyperalgesia - an increased sensitivity to pain, may be caused by damage to nociceptors or peripheral nerves. More extreme pain than allodynia

Hyperesthesia - a condition that involves an abnormal increase in sensitive stimuli of the senses (hear, touch, taste, etc) Increased touch sensitivity - tactile
hyperesthesia
Increased sound sensitivity - auditory hyperesthesia

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8
Q

Autonomic Terms

A

Vasomotor - dilation and constriction of blood vessels

Sudomotor - autonomic function associated with the sweat
glands

Trophic - changes in tissues, due to loss/reduction of nerve and/or blood supply (muscle atrophy, increased nail growth , changes in nails, increased hair growth (hypertrichosis)

  • Vasodilation - red swollen, as this progresses the vasodilation transitions to vasoconstriction - blue and stiff
  • Typically sweating comes early and lack of sweat later
  • Really dry skin and don’t sweat at all - they probably have a peripheral nerve issue (peripheral nerve autonomic role is to provide sweat in tissue)

Muscle atrophy occurs b/c of irritation but people who have this avoid movement

Body sends extra blood flow to nail and people don’t want to be touched so don’t cut nails

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9
Q

2 Types of CRPS

A

Type I: Occurs after an illness or injury that did not directly
damage the peripheral nerves of the affected limb

Type II: There is an identifiable peripheral nerve injury

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10
Q

Grades and Stages of CRPS

A

Grade 1: Algodystrophy (disruption of bone growth
combine with sympathetic symptoms).

Grade 2: Sympathetic dystrophy without pain

Grade 3: Sympathetic maintained pain

Stages - Time Frames:

Acute Phase: First 3 months (redness burning)

Subacute Phase: 3 more months (3-6 months)

Chronic Phase: 6 months onward (6-12 months)

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11
Q

Diagnostic Testing

A

Three phase bone scan to evaluate vascular profusion
Monitor digital pulp temp
X-Rays used to evaluate regional osteopenia
Infrared thermography imaging - diff in skin temp

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12
Q

Sympathetic Chain

A

Messages received from periphery are wrong - saying danger when there is not danger

Local issue but also brain is remapping and triggering fight or flight and brain shuts down area out of protection

Central sensitization - when threshold of the spinal cord in brain is lowered and takes less to fire pain receptors

Body can’t modulate for temperatures b/c they are not getting proper input so they can get frost bite in cold weather

Anxious person is at a higher risk

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13
Q

Evaluation and Identification of CRPS

A
  • Early dx is of utmost importance - the sooner proper tx is delivered the better
  • Mechanism of Injury - usually follows some type of trauma such as fx, sharp force injury, surgery, infections, heart problems and cumulative trauma disorders. Insult may be quite mild in nature.
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14
Q

Stage 1

A

Acute phase - beginning to 3 months

Clinical Presentation

  • Increased hair and nail growth
  • Changes in sweating
  • Increased pain
  • Skin becomes thin and dry
  • Color change red, warm, and swollen but may quickly become cold (depending on activity)
  • Can have swelling
  • Allodynia - NON painful stimuli evokes pain
  • Hyperalgesia - painful stimuli evokes more intense pain than usual
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15
Q

Stage 2

A

Sub-acute

  • 3-6 months
  • Decreased hair growth
  • Swelling could spread (can start going up arm)
  • Stiffness - even with PROM, changes process of tissue
  • Appearance
  • Joints thicken
  • Mm atrophy
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16
Q

Stage 3

A

Chronic phase
* 6 or more months
* Changes are irreversible - can’t do anything
* Severely limited mobility of affected area - permanent
contractures
* Contractures of the muscle and tendons that flex the jts
* Muscle wasting occurs during this stage

17
Q

Treatment

A

80% of those who receive treatment within the first year will have significant improvements

50% will improve if treatment is started within the second year

Good news we can help with this dx

No pain No gain does NOT work with CRPS

  • Modalities
  • Exercise
  • Edema Control (Massage/garments)
  • Stress Loading
  • Desensitization
  • Splinting is controversial
  • Functional Activities
  • Imagery and Relaxation
  • Mirror box
  • CPM

Need to move - usually short session of exercise thru day, if not moving it is the worst thing

Control Swelling - teach them how to do self retrograde massage and it gives them control (address it in mind and touch limb) b/c it can sometimes feel like the limb is not theirs

They don’t tolerate traction and stretch - splinting but flexion glove (isotoner glove with rubber bands) works better, traction on fingers can break up reflexive loop

Graded motor imagery - is wonderful

Continue passive motion machine - as long as they can tolerate it (moves the limb for them)

Grip usually sign affected due to proprioceptive dysfunction - can’t feel how hard they are gripping or weight bearing - can drop items often

18
Q

MCP Squeeze Test

A

Grasp MCP and lightly squeeze - if can’t tolerate it is positive
Record as positive if pt pulls away

19
Q

Drop and Swipe Test

A

Part 1: Alcohol swab package is opened and squeeze till alcohol drops on the affected limb. In 10-60 sec ask the pt what they feel. If pain is dramatically increased the pt is experiencing thermal hyperalgesia (positive - painful)

If cold/cool it is a normal response and not thermal hyperalgesia

Part 2: Swipe the alcohol pad lightly over the affected area If pt responds with increased pain or withdraws the limb or tells you to stop, they are experiencing mechanical hyperalgesia (positive - painful)

20
Q

OT Goals

A
  • Minimize edema
  • Normalize sensation
  • Increasing flexibility, ROM, coordination
  • Promote normal positioning
  • Decrease muscle guarding
  • Increase functional use to increase independence
  • Educate pt regarding the pain cycle, meds/pain management
  • Normal use of the affected part
  • Facilitate movement (cornerstone of treatment) - this is the main thing
21
Q

Contraindicated in Most Cases

TEST!!!!

A
  • PROM
  • Joint Mobilization
  • Splinting and casting to immobilize
    • Not recommended to immobilize the extremity as
      disuse and guarding exists with this condition

PROM until they can tolerate it without being painful - we can easily push the into an inflammatory response

Need to focus on things that they have control over first

Once system is normalized we can progress

22
Q

Patient Education

A
  • Pain may not be giving an accurate account of their tissue status. No need to fear that they are causing damage
  • Changes in the brain when subjects think differently about their pain
23
Q

Watson Carlson Stress Loading

A
  • Scrub and carry (compression and; distraction)
  • Dystrophile - device used to measure amount of weight
    bearing a person can perform
  • The goal is to bear as much weight as possible through
    the affected arm. Common for the pain and swelling to
    slightly increase 1st few days of the protocol, but positive
    results usually observed within the 1st wk of tx
  • Begin with 3 min/ 3 times a day and progress to 10-15 min
    3 times a day
  • Carry: The pt is asked to carry an object weighing 1-2 lbs
    during the day. This causes a distraction force on the
    limb

Active exercise requires stressful use of the UE without forcing joint motion

The results are based on the application of pressure or resistance to the hand

This increases the large fiber afferent impulses which in turn helps relieve pain

Stress loading may initially produce an increase in pain or swelling of the extremity after several days a decrease in symptoms will begin to be evident

24
Q

Stress Loading Activities

A
  • Scrubbing on a plywood board while in the quadruped position. Scrub every 2 hrs starting at 3-5 minutes and work up to 10 mins
  • Carrying a weighted bag in the affected hand. Grade up the weight as quickly as possible according to tolerance
  • Functional Activities: washing windows, wiping counters, ironing, scrubbing bath tile, carrying groceries, sanding wood
25
Q

Maladaptive Cortical Remapping

A

Disorganization of the cortical representation of the affected limb results in pain and dysfunction

With no intervention the homunculus will remain disorganized and potentially get worse

Good cortical remapping involves experienced based learning

26
Q

Graded Motor Imagery

A

Phase 1: Laterality
- Left/right discrimination is the accuracy and speed of
identifying whether a picture or body part is a R or L

  • This is done by having pt find the affected hand in
    every picture, turn photos in many directions. They
    have to develop this before doing graded motor
    imagery
  • Laterality is lost in pt with CRPS. The brain tunes out
    the effective limb
- Restores accuracy and speed of L vs R

- Phase 1 Laterality average time is 2.4 sec to point out
  the correct body part in normal population

- For someone with CRPS it takes twice as long to 
  recognize at 4.7 sec average
       tx is to get them to be able to correctly identify the 
       body part and not speed
  • Diaphragmatic Breathing - physiologically impossible to be in fight or flight
  • Meditation
  • Guided imagery
  • Biofeedback
27
Q

Phase 2

A

Imagery - imagine the extremities performing motion

             - static
             - dynamic
             - doing a task
  • This gives the brain map exercises without moving the extra sensitive extremity
28
Q

Phase 3: Mirror Therapy

A
  • Mirror conveys visual stimuli to the brain
  • Observation of one’s unaffected part
  • Principle states affected limb can be stimulated by visual
    cues originating from the opposite side of the body
  • MRI proves it does occur, firing of neurons on other side b/c brain thinks it is truly other limb
  • Static observation
  • Observe motion of non-affected extremity
  • Bilateral motion
29
Q

Exercises

A

Gentle AROM within tolerance

PROM can be performed once client can tolerate without system response

Strengthening in later stages as edema decreases and stiffness improves

If any increased pain and edema you have been too forceful or aggressive in your intervention choices

Exercise performed hourly and include all upper limb joints

30
Q

Therapy Interventions

A

Address Movement Disorders (dystonia and neglect):
PNF, stationary bike, UBE, Chinese meridian balls,
functional tasks, yoga, tai chi, dance - things that require
fluidity

31
Q

Modalities

A

Transcutaneous Electrical Nerve Stimulators (TENS)
and Functional Electrical Stimulation used to decrease pain, edema and increase muscle strength

Sends a superficial signal to brain - that sensation travels faster to the brain than pain and creates a traffic jam situation and allows them to move

32
Q

Modalities: Avoid Temperature Extremes in Early Phases of Intervention

A

Moist Heat - can increase tissue extensibility followed by exercise. Do not use in Stage 1 but add when they are stiffer

Whirlpool - have the pt perform exercise while their hand is under water. 10 min max

Fluidotherapy

Paraffin - only used in late stages of CRPS. Used in conjunction with passive stretch to increase joint mobility

Low Level Laser Light - stimulates healing, relieves pain without side effects

33
Q

Splinting

A

Use Caution - can Help or Hinder
* traction glove
* resting hand splint
* WARNING - splints immobilize joints and that is not good for CRPS
- may be important due to joint contractures that
develop
- person with stiff digits b/c of tone not necessarily injury
and traction helps break the stiffness up
- may have to build up splint wear time

34
Q

Therapy Intervention

A
  • Neutral Mobilization Techniques (passive motion) have to tolerate you touching them, if not you can teach them flossing this gives them more control and tend to respond better but compliance is the issue
  • Promote aerobic exercise and participation in normal life
    activities
35
Q

Medical Intervention

A
  • Let the Doctor know the symptoms you are observing as soon as possible
  • Don’t tell pt you think they have CRPS
  • Start implementing tx such as GMI
  • Only implement stress loading if it is safe to do so
  • Pain killers don’t work on neurogenic pain
  • Pharmacologic interventions are rarely used in isolation and are usually combined with therapy and adaptive modalities:
  • Anticonvulsants
  • Calcium Channel Blockers
  • Systemic corticosteroids
  • Antidepressants
  • Anti-inflammatory and Analgesics
  • Adrenergic
  • Serotonin re-uptake inhibitors
36
Q

Stellate Ganglion Nerve Blocks

A
  • Performed by anesthesiologist
  • When performed correctly causes drooping/ptosis of the
    eyelid
  • Pt must go to therapy right after the injection and must
    perform movement and exercises throughout the day
  • Usually a series of 5-6 injections

Stellate Ganglion Blocks - may be used to numb the stellar ganglion, a cluster of sympathetic Nn at the base of the neck, in an effort to reduce the over-activity of the sympathetic Nn

37
Q

Surgical Intervention

A
  • Decompression - can cut ganglion
  • Sympathectomy
  • Spinal Cord Stimulation - estem unit in spinal cord
  • Deep Brain Stimulation and Electrotherapy
  • All of these there is a risk