Complex Regional Pain Syndrome (CRPS)

Question 1

What is CRPS?

Answer 1

A chronic neuropathic pain that follows soft-tissue or bone injury (type I) or nerve injury (type II) and lasts longer and is more severe than expected for the original tissue damage.

Question 2

When does Stage 1 CRPS develop?

Answer 2

Most commonly after crush injuries, especially in a lower limb.

Question 3

What is the pathogenesis of CRPS?

Answer 3

Peripheral nociceptor and central sensitization and release of neuropeptides help maintain pain and inflammation

Question 4

What are some signs and symptoms of CRPS?

Answer 4

Pain has no pattern;
Burning or aching pain 
Worsen with changes in environment or emotional stress. 
Allodynia and hyperalgesia
Limit use of extremities because of pain