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BOARDS- IMMUNO > Complement > Flashcards

Complement Flashcards

1
Q

C5a

A

Neutrophil Chemotaxis

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2
Q

C3a, C4a, C5a

A

Anaphylaxis

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3
Q

C5b-C9

A

MAC lysis
Helps kill gram -ve bacteria
Gram -ve bacteria has T cell independant antigens (LPS - no polysaccrahide)

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4
Q

Complement Activation

A
  1. Antibody-antigen mediated (IgG, and IgM fix complement) –> C1
  2. Lecthin- microbial surface sugars activate C1 like intermediate –> C1
  3. Alternative pathway- microbial surface proteins–> C3b
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5
Q

Inhibitor of Complement to protect self

A

CD55- delay accelerating factor (GPI anchored enzyme - CD59)
C1 esterase inhibitor

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6
Q

C3b

A

opsonization

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BOARDS- IMMUNO (9 decks)

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