Autoantibodies Flashcards

1
Q

Anti-basement membrane

A

Goodpasture syndrome

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2
Q

Anticardiolipin, lupus anticoagulant

A

SLE, antiphospholipid syndrome

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3
Q

Anticentromere

A

CREST scleroderma

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4
Q

Anti-desmosome (anti-desmoglein)

A

Pemphigus Vulgaris

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5
Q

Anti-dsDNA, anti-Smith

A

SLE

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6
Q

Anti-glutamic acid decarboxylase

A

DM type 1

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7
Q

Antihemidesmosome

A

Bullous pemphigoid

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8
Q

Anti-histone

A

Drug induced lupus

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9
Q

Anti-Jo-1, anti-SRP, anti-Mi-2

A

Polymyositis, dermatomyositis

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10
Q

Antimicrosomal, antithyroglobulin

A

Hashimoto thyroiditis

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11
Q

Antimitochondrial

A

Primary biliary cirrhosis

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12
Q

Antinuclear antibodies

A

SLE, nonspecific

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13
Q

Antiparietal cell

A

Pernicious anemia

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14
Q

Anti-Scl-70 (anti-DNA topoisomerase I)

A

Diffuse Scleroderma

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15
Q

Anti-smooth muscle

A

Autoimmune hepatitis

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16
Q

Anti-SSA, Anti-SSB (anti-Ro, anti-La)

A

Sjogren syndrome

17
Q

Anti-TSH receptor

A

Graves

18
Q

Anti-U1 RNP (ribonucleoprotein)

A

Mixed connective tissue disease

19
Q

IgA anti-endomysial, IgA anti-tissue transglutaminase

A

Celiac disease

20
Q

MPO-ANCA/p-ANCA

A

Micoscopic polyangiitis, eosinophilic granulomatosis with polyangiitis (Churg-Strauss), Pauci-immune crescentic glomerulonephritis

21
Q

PR3-ANCA/c-ANCA

A

Granulomatosis with polyangiitis (Wegener)

22
Q

Rheumatoid factor, anti-CCP

A

Rheumatoid arthritis, Rheumatoid factor is IgM that targtes IgG Fc region, anti-CCP is more specific

23
Q

Anti-ACh receptor

A

Myasthenia Gravis