Comp 8 Endocrine Flashcards
signs of hypoglycemia
- HA
- dizziness
- confusion
- slurred speech
- nervousness
- anxiety
- agitation
- tremors, sweating, tachycardia, seizures
- appears “drunk”
signs of hyperglycemia
- extreme thirst
- dry mucous membranes
- poor skin turgor
- polyuria
- fruity breath
- fatigue, tachycardia, Kussmaul respirations
sulfonylureas action
stimulate beta cells in pancreas to increase insulin secretion
sulfonylureas SE
- hypoglycemia
- blood disorders
- photosensitivity
contraind to all oral antidiabetics
- known drug allergy
- severe kidney disease
- sever liver disease
- pregnancy
oral antidiabetics PT
- CA: BGM
- make sure PT tolerates food
- check with MD when PT is placed on NPO
- avoid alcohol
meglitinides action
-increase insulin secretion in pancreas
meglitinides SE
hypoglycemia
biguanide Metformin action and location
- decrease glucose production on the liver
- increase use of glucose by muscles and fat cells
Thiazolidinediones (TZDs) action and location
Decrease insulin resistance by stimulating receptors in muscle cells to uptake of insulin
Alpha-Glucosidase Inhibitors action and location
- Acarbose
- in GI, inhibits enzyme that breaks down carbohydrates, thus slows digestion
thyroid gland action
increases the metabolism in body -necessary for growth and development in children
Hypothyroidism SS
-fatigue, lethargy
- mental acuity
-personal and mental changes
-cold intolerance
-myxedema
-weight gain
facial puffiness
levothyroxine (Synthroid, Levothroid) action
- treat hypothyroid
- increase levels of t3 t4 thyroid hormones
levothyroxine CA
apical pulse and BP