Communicable Diseases Flashcards
Blood smear
Neutrophils - multi lobed
Lymphocytes - nucleus takes up most of space
Monocyte- biggest WBC , kidney bean shaped nucleus
Bacteria
Produce toxins
Plants - RING ROT - gram positive
+ TB
Viruses
Uncade living cells uses host cell to make new viruses + then burst out
Humans - HIV + FLU
plants - TMV
Proctist
May ned vector eg mosquito or aphids to transfer
Plant - potato blight
Human - Malaria
Fungi
Produce spores which can carry long distances
Plants - Black Sigatoka
Humans - athletes foot
How can malaria bypass primary defences
Pathogen directly into blood
Opsonin
Bind to pathogen , easily regcosinable to phagocytes, increase phagocytosis
Cytokines
Attracts phagocytes to site of
Processes that lead to production of antibodies
B cells carry antibody on surface complementary to one antigen
Selected B cell proliferates, differentiating into plasma cells + plasma cells release antibodies specific to antigen
Clonal
T cells - release interleukins which stimulates B cells to divide
Clonal selection + expansion
Diff strains mean
Each toxin diff 3D shape
Overview of how pathogen dealt w (cell mediated + hum oral immunity)
APC ingest antigen + display on surface , T helper cell binds to APC, production of interleukin
B cells activates , Clonal selection + expansion
P,lasmacells produce antibodies
This is NOT full process
Why is secondary immune response faster
Don’t have to wait for clonal selection, B memerky cells divide rapidly to produce plasma cells which produce right antibody