Common Skin Conditions - Acne Flashcards
List drugs that can discolor skin or secretions brownish
Levodopa
Entacapone
Methyldopa
List drugs that can discolor skin or secretions purple/orangish/reddish
Chlorzoxazone
List drugs that can discolor skin or secretions orange/yellowish
Sulfasalazine
List drugs that can discolor skin or secretions brownish/yellowish
Nitrofurantoin
Riboflavin (B12)
List drugs that can discolor skin or secretions blueish
Mitoxantrone
Methylene blue
List drugs that can discolor skin or secretions orange/reddish/brownish
Ezogabine
List drugs that can discolor skin or secretions brown/black/greenish
Methocarbamol
List drugs that can discolor skin or secretions yellow-greenish
Propofol
Flutamide
List drugs that can discolor skin or secretions red-orangeish
Phrnazopyridine
Rifapentine
Rifampin
List drugs that can discolor skin or secretions reddish
Anthracyclines
What’s the primary determinant of acne?
Androgens (male sex hormones) which is why boys often have worse acne than girls
List other factors that may contribute to acne
Presence of the bacteria P. acnes + fatty acids present in oil glands
List the 4 primary grps of acne agents
OTC (benzoyl peroxide and salicylic acid)
Retinoids
Systemic isotretinion
Antibiotics
What’s the most effective OTC acne agent?
Benzoyl peroxide (BPO)
What’s the usual rx drug of choice?
Retinoids, primarily topical tretinoin
How long does it usually take for retinoids to start working?
4-12 weeks
Acne may worsen initially
What’s usually given concurrently with retinoids to help with the worsening acne from initial retinoid use?
Antibiotic, usually Minocycline
What’s the brand name of Tretinoin microsphere gel?
Retin-A Micro
What’s the brand name of Tretinoin Polymerized cream or gel?
Avita
What’s the brand name of Adaplene?
Differin
How do u use retinoids?
A pea-sized amount is sufficient
Divide it into 4 equal parts
Smooth over the entire surface of the face- not just on acne
What should be avoided with Tretinoin use, especially while starting a retinoid (Retin-A Micro; Avita; Adapalene (Differing))? Why?
Avoid salicylic acid scrubs or astringents
May worsen irritation
How often should face be washed?
Wash with mild soap twice a day
T/F? Limit sun exposure while using retinoids (Retin-A Micro; Avita; Adapalene (Differing))?
True
What’s the preferred combo for acne?
Benzaclin (BPO) + 1% Clindamycin (Duac)
List clindamycin topicals
Cleocin T
ClindaMax lotion/soln
Clindagel
Evoclin foam
Benzamycine and Benzaclin
Howz Benzamycin and Benzaclin stored?
Benzamycin - refrigerated
Benzaclin - room temp
What’s the indication for oral isotretinion?
Only for tx of severe recalcitrant nodular acne
Contraceptions and oral isotretinion?
2 forms of birth control is required (NOT the mini pill)
What’s a bothersome side effect of oral isotretinion?
DRYNESS
Carry bottled water, eye drops and lip balm
What’s required b4 females can start oral isotretinion?
Must have 2 negative pregnancy test prior to starting tx
What meds are CI with oral isotretinion concurrently?
Vit A supplements
Tetracyclines
Steroids
Progestin-only contraceptives
St. John’s wort
What’s the preg category of oral isotretinion?
Cat X
Severe birth defects/ miscarriages
Where can oral isotretinion be dispensed?
Can only be dispensed by a pharmacy registered and activated with the pregnancy risk mgt IPLEDGE program
Which oral antibiotic is commonly used in acne?
Minocycline ext-rel (Solodyn)
What’s the brand name of Minocycline ext-rel (most commonly used Antiobiotic in acne)?
Solodyn
What other antibiotics are used for acne?
Doxycycline
Trimethoprim-Sulfamethoxazole
Is Aloe a natural pdt?
Yes
