Common Drugs That... Flashcards
1
Q
What are common drugs that cause diarrhoea?
A
- Antacids
- Metoclopramide
- PPIs
- Ranitidine
- Digoxin
- Metformin
- ACE-inhibitors
- Antibiotics
- SSRIs
- Colchicine
- Gliclazide
- Mesalazine
2
Q
Which drugs cause confusion (4)?
A
- Morphine sulfate
- Anticholinergics
- Antidepressants
- Anticonvulsants
3
Q
Which drugs cause hyperkalaemia?
A
- All heparins (eg. dalteparin) → inhibiton of aldosterone synthesis
- ACE-inhibitors
- Tacrolimus
- Aldosterone antagonists (eg. spironolactone)
- K-sparing diuretics
4
Q
Which drugs cause hypokalaemia?
A
- Loop diuretics
- Thiazide diuretics
- Insulin
- Acetazolamide
- Theophylline
- Prednisolone
5
Q
Which drugs cause urinary retention?
A
- Morphine sulphate
- Anticholinergics
- General anaesthesia
- Alpha-adrenoreceptor agonists
- Benzos
- NSAIDs
- Calcium channel blockers
- Antihistamines
- Alcohol
6
Q
Which drugs prolong the QTc interval?
A
- Antipsychotics (haloperidol, clozapine)
- Macrolide abx (erythromycin)
- Antifungal drugs (gluconazole)
- Anti-arrhythmic drugs (sotalol, amiodarone)
- Quinine
- Methadone
7
Q
Which drugs cause hyponatraemia?
A
- Loop diuretics
- Thiazide diuretics
- Carbamazepine
- Desmopressin
- Oxytocin
8
Q
Which drugs cause hypernatraemia?
A
- Lots of saline
- Mannitol
- Lithium
9
Q
Which drugs cause constipation (4)?
A
- Antimuscarinics → hyoscine / oxybutynin / tolterodine / TCAs + antipsychotics
- Cations → iron / calcium / aluminium (antacids)
- CCBs → verapamil
- Opioids
10
Q
Which drugs can induce seizures?
A
- Analgesics → opioids / LA toxicity / diclofenac / indomethacin / aspirin
- Abx → isoniazid / mefloquine / metronidazole / betalactams toxicity
- Antidepressants → bupropion / TCAs
- Antipsychotics → most, esp. clozapine
- Bronchodilators → theophylline / aminophylline
- Nicotine replacement → buproprion / vareniciline
