Common Conditions of the Eyes & Ears Flashcards
AD; AS; AU
AD= right ear
AS= left ear
AU- each ear
OD, OS, OU
OD= right eye OS= left eye OU= each eye
1 drop=
0.05 mL
ointments
apply to the conjunctival sac or over lid margins (for blepharitis). Ointments can make vision blurry. Do not use with contact lenses
gels
with caps on, invert and shake once to get the medication into the tip before instilling into the eye
glaucoma is…
a disease of the eye that results in damage to the optic nerve and loss of the visual field
In most cases of glaucoma, the intraocular pressure (IOP) is…
above the normal range of 12-22 mmHg
IP can be increased from…
genetics, age, and medications
Two main forms of glaucoma include…
1) open-angle (most common)
2) closed-angle (sharp, sudden increase in IOP due to a blockage. medical emergency that is treated surgically)
Prostaglandin (PG) analogs are used commonly as initial tx for glaucoma.
Decrease IOP by ~30%. MOA: increase aqueous humor outflow (move fluid out)
Ophthalmic beta-blockers (e.g. timolol)…
decrease IOP by 22%. Preferred if pressure is high in one eye only. MOA: reduce aqueous humor production (make less fluid).
Drugs that can increase IOP include:
- anticholinergics (e.g. oxybutynin, tolterodine, benztropine, trihexyphenidyl, TCAs)
- cough, cold and motion sickness meds (e.g antihistamines, scopolamine)
- chronic steroids, especially eye drops such as prednisolone (Pred Forte)
- topiramate (Topamax)
Prostaglandin analog dosing
1 drop QHS
Prostaglandin analog: warnings & side effects
Warnings- ocular effects: darkening of the iris, eyelid skin, and eyelashes; eyelash length and # can increase; contamination of multiple-dose ophthalmic solution can cause bacterial keratitis.
Side effects- Blurred vision, stinging, increased pigmentation of the iris/eyelashes, eyelash growth/thickening, foreign body sensation
Which prostaglandin analogs do not contain BAK (have a different preservative)?
- travoprost (Travatan Z)
- latanoprost (Xelpros).
- tafluprost (Zioptan)
Comes as 10 single-use, preservative-free containers in a foil pouch; discard each container after use.
Which prostaglandin analogs should be kept in the fridge before opening?
- latanoprost (Xalatan, Xelpros)
- latanoprostene bunod (Vyzulta)
- tafluprost (Zioptan)
bimatoprost
Lumigan
latanoprost
Xalatan, Xepros
latanoprost + netarsudil
Rocklatan
travoprost
Travatan Z
bimatoprost (Latisse)
Indicated for eyelash hypotrichosis (inadequate growth of eyelashes) to increase growth; do not use with prostaglandin analogs indicated for glaucoma
timolol 0.25% and 0.5% (Timoptic, Timoptic-XE, Istalol, Timolol GFS, Betimol, Timoptic Ocudose)
Timolol: 1 drop daily or BID
Timoptic-XE, Timolol GFS (gels): daily. Counsel to shake once before use; wait 10 min after giving other eye drops before inserting gel
timolol + dorzolamide
Cosopt, Cosopt PF (preservative-free)
timolol + brimonidine
Combigan
betaxolol (only selective BB). Less likely to cause pulmonary adverse effects in patients with chronic lung disease (ex. asthma/COPD)
Betoptic S
carteolol
Ocupress