Common Autoantibodies Flashcards

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1
Q

Rheumatoid Factor (4)

A

RA, SLE, Sjogren’s, mixed connective tissue disease

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2
Q

Anti-cyclic citrullinated peptide 2

A

Rheumatoid Arthritis

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3
Q

ANA (7)

A

Drug-induced lupus, SLE, scleroderma, Sjogren’s, MCTD, polymyositis/dermatomyositis, RA

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4
Q

Anti-dsDNA

A

Very specific for SLE

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5
Q

Antihistone

A

Drug-induced lupus

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6
Q

Anti-sm

A

Very specific for SLE

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7
Q

Anti-Ro/Anti-La

A

Sjogren’s

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8
Q

Antiphospholipid

A

Primary antiphospholipid syndrome

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9
Q

Anticentromeric

A

Scleroderma

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10
Q

Anti-topo-I (anti-Scl-70)

A

Scleroderma

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11
Q

Anti-Jo1

A

Polymyositis/dermatomyositis

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12
Q

Anti-thyroid peroxidase

A

Hashimoto’s

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13
Q

Anti-smooth muscle

A

Autoimmune Hepatitis

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14
Q

Antimitochondrial

A

Primary biliary cirrhosis

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15
Q

c-ANCA

A

Wegener’s granulomatosis

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16
Q

p-ANCA

A

Vasculitis, microscopic polyangitis

17
Q

Anti-GBM

A

Goodpasteure’s

18
Q

Antitransglutaminase

A

Celiacs

19
Q

Complement C3/C4 (decreased levels)

A

SLE, cryoglobulinemia

20
Q

antitopoisomerase

A

scleroderma

21
Q

Anti-TSHR

A

Graves Disease

22
Q

U1RNP antibody

A

MCTD