Common Autoantibodies Flashcards
1
Q
Rheumatoid Factor (4)
A
RA, SLE, Sjogren’s, mixed connective tissue disease
2
Q
Anti-cyclic citrullinated peptide 2
A
Rheumatoid Arthritis
3
Q
ANA (7)
A
Drug-induced lupus, SLE, scleroderma, Sjogren’s, MCTD, polymyositis/dermatomyositis, RA
4
Q
Anti-dsDNA
A
Very specific for SLE
5
Q
Antihistone
A
Drug-induced lupus
6
Q
Anti-sm
A
Very specific for SLE
7
Q
Anti-Ro/Anti-La
A
Sjogren’s
8
Q
Antiphospholipid
A
Primary antiphospholipid syndrome
9
Q
Anticentromeric
A
Scleroderma
10
Q
Anti-topo-I (anti-Scl-70)
A
Scleroderma
11
Q
Anti-Jo1
A
Polymyositis/dermatomyositis
12
Q
Anti-thyroid peroxidase
A
Hashimoto’s
13
Q
Anti-smooth muscle
A
Autoimmune Hepatitis
14
Q
Antimitochondrial
A
Primary biliary cirrhosis
15
Q
c-ANCA
A
Wegener’s granulomatosis