Common ABx for Infections

Question 1

Key principles for ABx

Answer 1

Send samples for culture and sensitivity only if you expect the results to change management
-cultures are GOLD STANDARD for microbe identification
Empirical => specific
Allergies!

PO whenever possible
Ensure course completed

Question 2

Specific ABx used for

• G+ve
• G-ve
• anaerobes
• systemic fungi

Answer 2

G+ve => penicillin, coamox, cefazolin
G-ve => cefepime, meropenem
Anaerobes => metronidazole
Systemic fungi => amphotericin

Question 3

Chest infections

• CURB 65 = 2
• CURB 65 3+

Answer 3

BOTH FOR 7 DAYS

CURB65 = 2
-Amox/ceftriaxone + clarithromycin PO

CURB65 = 3+
-coamox IV/ceftriaxone IV + clarithromycin

Question 4

Trauma and orthopedics infections management

-acute septic arthritis, osteomyelitis

Answer 4

42 days

Fluclox IV/teicoplanin IV + gentamicin IV

Question 5

Cellulitis ABx management

• mild/moderate
• severe
• severe/systemic

Answer 5

7 DAYS
Mild/moderate
-fluclox/claithromycin

Severe
-ceftriaxone IV

Severe/systemic
-penicilin G IV + fluclox IV OR teicoplanin IV

Question 6

ENT

• acute localised otitis ext
• acute diffuse otitis ext
• acute otitis media

Answer 6

7 days
Acute localised otitis ext
-fluclox/clarithromycin
Acute diffuse otitis ext
-cipro

5 days, not to be given if uncomplicated
Acute otitis media
-amox/clarithromycin
-coamox/doxy + metronidazole

Question 7

ENT

-pharyngitis/tonsilitis (mild, moderate/severe)

Answer 7

Pharyngitis/tonsilitis
Mild - phenoxymethyl penicilin/clarithromycin

Moderate/severe - Penicillin G IV/clindamycin IV + metronidazole IV
-SAME AS PERITONSILLAR ABSCESSES

Question 8

ENT - epiglottitis

Answer 8

7-10 days

Ceftriaxone IV/clindamycin IV with ciprofloxacin