COMbank Flashcards
when triaging patients in multi person injury accidents, First priority patients are color coded what?
Red, indicating they need immediate life saving treatment
when triaging patients in multi person injury accidents, Second priority patients are color coded what?
Yellow to indicate that they require urgent medical care within 2-4 hours
when triaging patients in multi person injury accidents, patients who appear to have minimal injuries such as the child are treated last, regardless of age. Third priority is color coded what?
green, they need medical treatment, but it can be safely delayed
when triaging patients in multi person injury accidents, Patients that are deceased or have minimal chance of salvage are not treated. These patients are color coded what?
black
Door to needle time for fibrinolytic therapy in STEMI when PCI not available needs to be less than how long
< 30 min
This is an acquired benign dermatologic condition that appears suddenly as an itchy papular rash over the trunk. It is most commonly seen in men over the age of 50. The rash usually appears as small, red papules on the central back or mid-chest regions. It has been associated with sweating, sun exposure, heat, and ionizing radiation.
Grover disease (transient acantholytic dermatosis)
What are histologic findings of Grover disease
focal acantholysis and dyskeratosis
Describe the disease progression of Grover disease
- The disease is self-limiting; patient should be educated to avoid excessive sweating and sun exposure
- A topical steroid can be used for symptomatic relief
Symptoms of this include hemorrhagic blisters, milia, scarring, dyspigmentation, and hypertrichosis localized to the dorsal hand and forearms
Porphyria cutanea tarda which results from deficiency of hepatic uroporphyrinogen decarboxylase, an enzyme involved in the metabolism of heme
Specific antibody for pemphigus vulgaris
anti-desmoglein 3
This is an autosomal dominant disease due to a mutation in ATP2C1, a calcium ATPase pump. It is characterized by the presence of vesicular lesions and crusting erythematous plaques over intertriginous areas including the genitals, inguinal area, sometimes extending onto the thigh, as well as the chest, neck, and axilla. Burning and pruritis accompany the eruption, as well as a MALODOROUS drainage that may occur from secondary bacterial infections
Familial benign pemphigus (Hailey-Hailey disease)
Both ALS and syringomyelia can present with both UMN and LMN signs . . how do you tell difference?
ALS is a pure muscle disorder . . no sensory changes
-ALS also, almost always begins Asymmetrically
What are common somatic findings associated with migraines.
Abnormal strain patterns at the SBS and cervical or upper thoracic spine dysfunction
Osteoporosis may be diagnosed how?
when dual-energy x-ray absorptiometry scan results show a bone mineral density of 2.5 standard deviations or more below peak bone mass (T score ≤ -2.5), OR with history of a fragility fracture ***
Patients with meconium aspiration syndrome (MAS), are at increased risk of developing persistent what?
pulmonary hypertension (PPH).
All infants and toddlers should ride in a rear-facing car safety seat until what age?
2 years or have reached the manufacturer’s max limit
All children 2 years or older should use what type of car riding safety?
Forward-Facing car safety seat with harness for as long as possible
At what size and age should children be restrained in the rear seats always using lap and shoulder seat belts
-typically 4 feet 9 inches and are between 8 and 12 years of age
All children younger than 13 years should be restrained where in a vehicle
rear seat
All children who have reached the weight or height limit for their forward facing car safety seat should be seated in what? . . . Most 5 year olds will have outgrown a child safety seat but will not be tall enough to fit correctly in a lap and shoulder belt
A belt-positioning Booster seat until the vehicle seat belt fits properly
Budd-Chiari syndrome, or hepatic venous outflow obstruction is most commonly caused by polycythemia vera . . what are he classic findings of polycythemia vera
- pruritis
- Blurry vision
- Erythromelalgia (burning in the hands and feet followed by a blue or red discoloration)
What is the imaging modality of choice in diagnosing Budd-Chiari syndrome.
Doppler ultrasonography
What does doppler US show in Budd-Chiari syndrome?
Positive findings include inability to visualize the junction of the major hepatic veins with the inferior vena cava, thickening or stenosis of the hepatic veins, or abnormal flow in the hepatic veins or inferior vena cava.
Describe the use of venography in the diagnosis of Budd-Chiari syndrome
Venography is the gold standard for diagnosing Budd-Chiari syndrome. It is critical in assessing full extent of disease and optimal treatment. However, due to its invasiveness it can only be performed if other noninvasive tests are not diagnostic or negative with a strong clinical suspicion for disease.
Management of Budd-Chiari syndrome
Should attempt medical therapy (eg, anticoagulant and diuretic) before surgical intervention (stent)
Describe the management when IUD string cannot be seen
- US first to confirm position
- Flat plate x-ray if position is not confirmed in uterus
This condition involves osteochondrosis of the second metatarsal head and is most frequently encountered in adolescents and young females.
Freiberg’s infraction
This traction apophysitis at the insertion of the Achilles on the calcaneus and is most common during periods of rapid physical growth, e.g. puberty.
Sever’s Disease
This condition involves a traction apophysitis at the INFERIOR POLE OF THE PATELLA. Osgood-Schlatter affects the tibial tuberosity rather than the inferior pole of the patella. As with other similar conditions, it is most frequently encountered during periods of rapid growth (e.g. puberty).
Sinding-Larsen-Johansson syndrome
Treatment of Sjogren
-Pilocarpine or cevimeline
Hemodialysis should be performed in patients with methanol poisoning who meet the following criteria
1) Ingestion of methanol volumes greater than 30 mL
2) Serum methanol levels of 20 mg/dL or greater
3) Development of visual changes
4) Lack of acidotic improvement despite multiple sodium bicarbonate infusions
Metformin cannot be used in patients with a GFR under what
30
This is characterized by a rigid thoracic kyphosis, vertebral wedging, and degenerative end plates. It is diagnosed by radiograph, and anterior wedging > 5 degrees must be seen in at least 3 adjacent vertenbrae.
Scheuermann kyphosis
What is best treatment for Scheuermann kyphosis in a mature adult
OMM and PT
What is the most common risk factor in ectopic pregnancy
PID
This is a mental disorder characterized by repeated regurgitation of chewed food. Food is regurgitated, swallowed or spit out. A patient must demonstrate this activity for at least one month. PE is remarkable for raw and chapped lips, bad breath, tooth decay, and weight loss. It is more common in infants or very young children
Rumination disorder
Describe the management of a polyp detected incidentally on annual screening colonoscopy
multiple biopsies or polypectomy
Oculomotor nerve palsy can occur with subarachnoid hemorrhage, most commonly when there is a ruptured aneurysm of what artery?
Posterior communicating artery
The anterior communicating artery is the most common site for aneurysm formation. What is it likely to compress leading to what symptoms?
- Optic chiasm
- Bitemporal heteronymous hemianopsia
The most common cause of subarachnoid hemorrhage is a ruptured berry aneurysm. The definitive treatment to prevent rebleeding is what?
endovascular coiling
Pedal edema in Rocky mountain spotted fever?
common in children
Homocysteine in folated and B12 deficiency?
elevated in BOTH
Le Fort fractures are fractures of the midface and are broken into I, II, and III. Describe a Le Fort I fracture
- Involve only the maxilla at the level of the nasal fossa
- Classically this occurs from a direct facial blow
- placing the central incisors between a gloved index and thumb and then moving anterior-posterior, slight mobility will be observed
- No other mobility of the nasal bones or zygoma is present
Le Fort fractures are fractures of the midface and are broken into I, II, and III. Describe a Le Fort II fracture
- involves the maxilla, nasal bones, and the medial aspects of the orbits
- PE will reveal and unstable maxilla as in a Le Fort I, but will also have nasal bone mobility
- In severe, CSF rhinorrhea may be present
Le Fort fractures are fractures of the midface and are broken into I, II, and III. Describe a Le Fort III fracture
- Most serious and is complete craniofacial disjunction
- It involves the maxilla, zygoma, nasal bones, and can include bones of the cranial base
- So severe that often airway compromise occurs from facial hemorrhage
- PE will reveal an unstable entire midface moving the maxilla will result in “floating” of the face from the rest of the head.
- In addition, Trismus, malocclusion, and CSF rhinorrhea may all be present
If a patient in status epilepticus does not respond to lorazepam, then what should be administered?
Phenytoin
If a patient in status epilepticus does not respond to lorazepam and then also not to phenytoin, what do you give next?
phenobarbital, pentobarbital, midazolam, or propofol can be tried
First line treatment for CAP in an outpatient setting
Macrolide or tetracyclines
what is the gold standard for diagnosing acute cholecystitis
Hepatobiliary iminodiacetic acid scanning (HIDA)
Best screening test fo acute cholecystitis
Abdominal US
What finding on HIDA is suggestive of cholecystitis
- A radioactive tracer is injected into any accessible vein and allowed to circulate to the liver whee it will be excreted in bile
- A normal filling time for the gallbladder is 35-45 minutes
- Failure to fill or delayed filling is suggestive of cholecystitis
ERCP and MRCP can be used to confirm what
choledochlithiasis
Cobb angle between 10 and 20 degrees in skeletally immature patients can be managed how?
- home exercises
- observation and serial radiographs every 6-12 months
Cobb angle between 20 and 45 degrees in skeletally immature patients can be managed how?
-bracing and serial monitoring
Cobb angle >45 degrees in skeletally immature patients can be managed how?
surgical fusion
Alport syndrome is a hereditary form of glomerulonephritis caused by a defect in what?
type IV collagen
Glomerular basement membrane splitting
alport syndrome
Spike and dome appearance . . . . what glomerular disease
- due to granular deposits of IgG and C3
- Membranous nephropathy
Tram Track appearance of the basement membrane . . what glomerular disease
- due to subendothelial and mesangial deposits
- Membranoproliferative nephropathy
After an ECG, patients with stable angina should have what tests?
- Transthoracic Echo or
- radionuclide myocardial perfusion imaging (if can’t exercise)
Cervical cytology revealing HSIL in pregnancy must be evaluated with what
colposcopy
Most accurate diagnostic test for mitral regurg
transESOPHAGEAL echo
Neonatal mass through abdominal wall that is edematous, dark in color, and typically appears to be covered by a gelatinous matrix of greenish material
Gastroschisis
what food recommendation reduces gout flares
Low-fat diary products and vegetables
What is the best medication with the least side effects used to manage acute presentation of gout
NSAIDs
Colchicine was the mainstay of treatment of acute gout flares in the past. However, it is rarely used because of its high side effect profile. Describe its MOA and side effects?
- decreases leukocyte motility (and thus inflammatory response)
- N/V
- Diarrhea
- Bone marrow suppression
- thrombocytopenia
Cardiac sympathetic fibers originating on the left primarily innervate what?
- Left side of heart
- AV node
Cardiac sympathetic fibers originating on the right primarily innervate what?
- right side of heart
- SA node
NMDAR encephalitis . . confirmed with detection of antibodies for the NMDA receptor (either in serum or CSF) . . in a young women it is associated with what?
- Ovarian teratoma
- Get Pelvic US or CT
Describe what the double density sign in Mitral stenosis is?
- Seen as 2 densities near the right heart border
- Caused by enlargment of the left atrium and leading to a rightward displacement of the right wall of the left atrium such that it pushes into the adjacent right lung and may become superimposed or even pass beyond, the normal borders of the right atrium on chest x-ray
What is the most common cause of endocarditis, even in patients with a known history of GI malignancies such as colon cancer
Staph aureus is still most common
ALS is the most common progressive motor neuron disease. Dx is largely based on history, PE, and what studies?
EMG studies
The ulnar nerve can be entrapped at the wrist (Guyon’s canal) or elbow (cubital tunnel). How do you distinguish?
-Cubital tunnel: No pain or trauma to elbow. decreased sensation to dorsum of hand
What is the first line treatment for newly diagnosed gestation diabetes?
- A trial of diet and exercise
- If this alone does not adequately control serum glucose levels, then therapy with insulin should be initiated
Children with ADHD are at an increased risk of having what psychiatric diagnosis later?
Antisocial personality disorder
What is the method of detecting semen in a sexual assault case
Wood’s UV light lamp
Most common site of vaginal trauma in sexual assault
Posterior forchette
Treatment of Bell’s palsy
Glucocorticoids and eye care
Possible lab findings in Sarcoidosis
- Increased ACE secondary to being secreted from non-caseating granulomas
- Also secrete 1,25 vitamin D resulting in Hypercalemia and hypercalciuria
Mainstay therapy for sarcoidosis
Corticosteroids
Treatment of Granulomatosis with polyangiitis
Corticosteroids and oral cyclophosphamide
What acute transfusion reaction?
- Fever
- Hypotension
- Flank/back pain
- Decrease in Hbg
Acute hemolytic
What acute transfusion reaction?
- Bronchospasms
- Hypotension
- Angioedema
Anaphylaxis
-Most common with IgA deficiency
What acute transfusion reaction?
- Fever
- No other symptoms
- Febrile non-hemolytic
- Dx of exclusion, cytokines released from WBC during storage stimulate fever
- Risk reduced with leukoreduced RBCs
What acute transfusion reaction?
- Fever
- Hypotension
- Sepsis secondary to bacterial transmission
- More commonly occurs in platelet transfusions (stored at room temp)
What acute transfusion reaction?
- Respiratory distress
- No fever
- TACO (Transfusion associated circulatory overload)
- Occurs with large numbers of transfusions or hx of heart failure
What acute transfusion reaction?
- Fever
- Respiratory distress
- Hypotension
- TRALI (Transfusion related acute lung injury)
- Occurs during or within 6 hours of transfusion
- Occurs when transfusion recipients’ neutrophils in lungs are activated by transfused product
Describe the relationship between Hyperventilation syndrome (tachypnea and hyperpnea) and Calcium
- Respiratory alkalosis
- As C02 drops, hydrogen ions are released from their binding sites on albumin
- Now albumin can bind calcium leading to hypocalcemia
What levels are useful in diagnosing Congenital adrenal hyperplasia
17-hydroxyprogesterone
first line treatment for congenital adrenal hyperplasia?
Glucocorticoids
Fever of unknown origin is a term used to describe prolonged fevers of > 101 F with no established dx despite a thorough evaluation. What are leading causes
- collagen vascular disorders
- Infections
- Malignancies
What is the criteria for metabolic syndrome
- Abdominal obesity > 40 inches in men or > 35 inches in women
- Triglycerides > 150
- HDL < 40 in men and < 50 in women
- Blood pressure > 130/85 or on HTN meds
- Fasting glucose > 100 mg/dL
- Must have 3/5
Exercise induced bronchoconstriction frequently presents during athletic participation and/or exercise. Spirometry usually gives a normal result. What is the diagnostic test
Bronchial provocation testing
First 2 meds to give patient post MI with acute systolic heart failure
ACEI and beta blocker
The evidence for systolic heart failure shows mortality benefit for only what 3 beta blockers
- Metoprolol succinate
- Carvedilol
- Bisoprolol
Stages/time frame of alcohol withdrawal
1) 6-12 hours: tremor, tachycardia, HTN
2) 12-24 hours: seizures
3) 2-7 days: DTs
Hypotonia with hyperreflexia is an early feature of what disease that causes dementia
Huntington disease
is there a coorelation b/t alcohol and pancreatic cancer
no . . . smoking is tho
Another name for anterior spinal artery syndrome
Beck’s syndrome
Acceptable blood pressure in patients 60 or older is what?
less than 150/90
Describe the colon cancer screening of a patient with a first degree relative with colon cancer
colonoscopy every 5 years beginning 10 years earlier than the age at which the relative was diagnosed or age 40 . . whichever is earlier
Uptake in Graves?
diffuse
This is otherwise known as toxic multinodular goiter. 2nd most common cause of hyperthyroid. A radioactive iodine thyroid scan and uptake tests shows patchy or localized uptake
Plummer’s disease
This is defined as low serum thyrotropin (TSH) with normal thyroid hormone levels
Subclinical hyperthyroidism
Describe the Rai staging system in CLL
Stage 0: Lymphocytosis > 15,000 Stage 1: Lymphocytosis + lymphadenopathy Stage 2: lymphocytosis + splenomegaly Stage 3: lymphocytosis + anemia Stage 4: lymphocytosis + thrombocytopenia
Giant cells with bilobar nuclei and eosinophilic nucleoli are also known as what?
associated with what dz?
- Reed-Sternberg cells
- Hodgkin’s disease
These are PAS staining IgM deposits around the nucleus and may be seen within plasma cells of marrow aspirates?
Associated with what dx?
- Dutcher bodies
- Waldenstrom’s macroglobulinemia
Plasma cells with a fried egg appearance
Multiple Myeloma
Suspect dermatomyositis in a patient with proximal muscle weakness that presents with skin manifestations over the knuckles (Gottron’s papules) and eyes (heliotrope purple rash). What may also be seen in the subcutaneous fatty tissue?
calcifications
What is the preferred method to evaluate centrally located lung lesions?
Fiberoptic bronchoscopy
What is the preferred method for evaluation of peripheral lung lesions
CT-guided biospy
What is the most sensitive physical exam test for an acute ACL tear?
Lachman test
Why is anterior drawer test not the best test for assessing ACL integrity
Because the knee is in 90 degrees flexion, other soft tissue structures are stabilizing the knee
Progression of osteoarthritis treatment?
first: exercise and weight loss
second: acetaminophen
third: NSAIDS
you know the rest
A patient with a recent travel history, who presents with severe systemic flu-like symptoms, rose spots and splenomegaly is most likely presenting with what?
Typhoid fever caused by Salmonella typhi.
Vibrio parahemolyticus can cause similar symptoms as Salmonella typhi but is associated with the ingestion of what
seafood
What is Waddell’s signs?
What disorder does it signify?
Basically it’s a bunch of ways to tell if a patient complaining of back pain is malingering
what sex cord testicular tumor is associated with Peutz-Jeghers and Carney’s syndrome.
Sertoli cell
The inferior glands of the parathyroid are derived from the what pharyngeal pouch. This structure is also the embryologic origin of the thymus.
third
Describe the PT, PTT, and bleeding time in von Willebrand’s disease
- Platelet counts and PT normal
- PTT will be prolonged due to the decreased level of factor VIII
- Bleeding time prolonged due to platelet defect
This test can measure the capacity of vWF to agglutinate platelets and is used in the diagnosis of VWD.
A ristocetin cofactor assay of the patient’s plasma
What test evaluated for the presence of a completely ruptured achilles tendon?
Explain the text?
- Thompson test
- Patient prone with feet hanging over the end of table
- The affected calf is squeezed, if torn then no planarflexion
Describe the non-operative treatment for acute Achilles tendon rupture?
- immobilization in 20 degrees of plantarflexion for 2 weeks**
- Followed by functional bracing with limited dorsiflexion, protected weight bearing, and PT
Normal UA but elevated proteins on 24 hours protein:creatinine ratio?
- MM
- if nephrotic syndrome then Albumin would be detected on dipstick UA
Lipids and nephrotic syndrome?
Hyperlipidemia
This involves tendinopathy of the pelvic stabilizers at the confluence of the rectus abdominis insertion, adductor origin, and pelvic floor at the pubic ramus
Athletic pubalgia
Another name for Milk-alkali syndrome
Burnett syndrome
What is SIRS criteria
- 2 or more of the following
- Fever > 38 C (100.4 F) or < 36 C (96.8)
- HR > 90
- RR > 20 or PaCO2 < 32
- WBC > 12k or < 4 K or > 10% bandemia
This is defined as meeting SIRS criteria plus a suspected source of infection
Sepsis