Colorful Anemia Chartizzle Flashcards
List the microcytic anemias
T: Thalassemia A: Anemia of Chronic Disorders I: Iron deficiency L: Lead poisoning S: hereditary spherocytosis S: Sideroblastic Anemia
List the microcytic hemolytic anemias
Hereditary spherocytosis
Thalassemia
List the Macrocytic anemias
B12 deficiency
Folate deficiency
List the Hemolytic anemias
Hereditary spherocytosis
Thalassemia
G6PD
AIHA
PK Def
Sickle Cell
Normocytic/Random Anemias
Anemia due to renal dysfunciton
Endocrine related anemia
Sideroblastic
Malnutrition
Menstrual loss, bleeding, dietary intake, absorption issues, cancer, pregnancy can cause which anemia?
Iron Deficiency
Chronic inflammation (too much damage), alcoholism, malignancy can cause which anemia?
Anemia of Chronic Disease
Exposure to lead including eating paint chips can cause which anemia?
Lead intoxication
Mutated proteins cause weakened membrane (spectrin, ank, band 3) and spherocyte formation. Autosomal dominant mode of inheritance. can cause which anemia?
Hereditary Spherocytocis
Different hemoglobin chains present than normal- Autosomal recessive disorders can cause which anemia?
Thalassemia
Vegan diet, pernicious anemia (autoimmune destruction of Intrinsic factor cells), failure to produce IF, malabsorbtion, defective transport or storage, metabolic pathway deficits can cause which anemia?
B12 Deficiency
Alcoholism, overcooking food, malabsorbtion, inadequate intake, parasitic infection, pregnancy, drink lots of goats milk can cause which anemia?
Folate deficiency
X-linked recessive enzyme deficiency (males affected), triggered by lots of foods (fava beans) and chemicals can cause which anemia?
G6PD Deficiency
Infection, malignancy, autoimmune, drugs can cause which anemia?
Autoimmune Hemolytic Anemia
Second most common enzyme deficiency anemia
PK deficiency
Genetic mutation causing a Glu->Val transformation on hemoglobin leading to sickled RBC’s and hemolysis can cause which anemia?
Sickle Cell
Renal dysfunction. can cause which anemia?
Anemia due to renal dysfunction
Chronic alcoholism, B6 deficiency, Lead poisining, hereditary or acquired (X linked recessive) can cause which anemia?
Sideroblastic (Deposits of iron in mitochondria of erythroid precursors)
Signs and symptoms of Hereditary spherocytosis
Anemia, jaundice, splenomegaly, hyperbilirubinemia as neonates, can lead to aplastic crisis and biliary stones
Signs and symptoms of Thalassemia
Splenomegaly,
expanded bone marrow,
delayed growth and development, endocrinopathies,
pulmonary hypertension
Signs and symptoms of B12 Deficiency
Neurologic deficits, slow onset, smooth, sore tongue
Signs and symptoms of Folate deficiency
slow onset, smooth, sore tongue
Same as B12, minus neurological symptoms, rapid onset
Signs and symptoms of G6PD deficiency
Acute hemolytic anemia,
hyperbilirubinemia,
variable degrees of anemia
Signs and symptoms of Autoimmune Hemolytic Anemia
acute or chronic onset of anemia, pallor jaundice dark urine. Splenomegaly may occur. Positive DAT test (direct coombs)
Signs and symptoms of PK deficiency
hemolysis,
splenomegaly,
gallstones
aplastic crises
Signs and symptoms of Sickle cell anemia
Vessel damage leading to multi-organ damage (lungs, retina, spleen, kidney, CNS),
priaplasm, and
aplastic crisis
Signs and symptoms of Anemia due to renal dysfunction
Prolonged bleeding time, fatigue, pallor, decreased exercise tolerance, dyspnea, tachypnea
Signs and symptoms of Endocrine related anemia
Thyroid: Hyper or hypactivity, weight gain or loss, skin, hair nail changes, Adrenal: vomiting dehydration weakness, circulatory collapse
List the organs associated with absorption
D J I
I F B
