Colorful Anemia Chartizzle Flashcards

1
Q

List the microcytic anemias

A
T: Thalassemia
A: Anemia of Chronic Disorders
I: Iron deficiency
L: Lead poisoning
S: hereditary spherocytosis
S: Sideroblastic Anemia
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2
Q

List the microcytic hemolytic anemias

A

Hereditary spherocytosis

Thalassemia

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3
Q

List the Macrocytic anemias

A

B12 deficiency

Folate deficiency

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4
Q

List the Hemolytic anemias

A

Hereditary spherocytosis
Thalassemia

G6PD
AIHA
PK Def
Sickle Cell

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5
Q

Normocytic/Random Anemias

A

Anemia due to renal dysfunciton
Endocrine related anemia
Sideroblastic
Malnutrition

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6
Q

Menstrual loss, bleeding, dietary intake, absorption issues, cancer, pregnancy can cause which anemia?

A

Iron Deficiency

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7
Q

Chronic inflammation (too much damage), alcoholism, malignancy can cause which anemia?

A

Anemia of Chronic Disease

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8
Q

Exposure to lead including eating paint chips can cause which anemia?

A

Lead intoxication

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9
Q

Mutated proteins cause weakened membrane (spectrin, ank, band 3) and spherocyte formation. Autosomal dominant mode of inheritance. can cause which anemia?

A

Hereditary Spherocytocis

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10
Q

Different hemoglobin chains present than normal- Autosomal recessive disorders can cause which anemia?

A

Thalassemia

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11
Q

Vegan diet, pernicious anemia (autoimmune destruction of Intrinsic factor cells), failure to produce IF, malabsorbtion, defective transport or storage, metabolic pathway deficits can cause which anemia?

A

B12 Deficiency

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12
Q

Alcoholism, overcooking food, malabsorbtion, inadequate intake, parasitic infection, pregnancy, drink lots of goats milk can cause which anemia?

A

Folate deficiency

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13
Q

X-linked recessive enzyme deficiency (males affected), triggered by lots of foods (fava beans) and chemicals can cause which anemia?

A

G6PD Deficiency

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14
Q

Infection, malignancy, autoimmune, drugs can cause which anemia?

A

Autoimmune Hemolytic Anemia

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15
Q

Second most common enzyme deficiency anemia

A

PK deficiency

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16
Q

Genetic mutation causing a Glu->Val transformation on hemoglobin leading to sickled RBC’s and hemolysis can cause which anemia?

A

Sickle Cell

17
Q

Renal dysfunction. can cause which anemia?

A

Anemia due to renal dysfunction

18
Q

Chronic alcoholism, B6 deficiency, Lead poisining, hereditary or acquired (X linked recessive) can cause which anemia?

A

Sideroblastic (Deposits of iron in mitochondria of erythroid precursors)

19
Q

Signs and symptoms of Hereditary spherocytosis

A
Anemia,
 jaundice, 
splenomegaly, 
hyperbilirubinemia as neonates, 
can lead to aplastic crisis and biliary stones
20
Q

Signs and symptoms of Thalassemia

A

Splenomegaly,
expanded bone marrow,
delayed growth and development, endocrinopathies,
pulmonary hypertension

21
Q

Signs and symptoms of B12 Deficiency

A

Neurologic deficits, slow onset, smooth, sore tongue

22
Q

Signs and symptoms of Folate deficiency

A

slow onset, smooth, sore tongue

Same as B12, minus neurological symptoms, rapid onset

23
Q

Signs and symptoms of G6PD deficiency

A

Acute hemolytic anemia,
hyperbilirubinemia,
variable degrees of anemia

24
Q

Signs and symptoms of Autoimmune Hemolytic Anemia

A
acute or chronic onset of anemia, 
pallor 
jaundice
dark urine. 
Splenomegaly may occur. 
Positive DAT test (direct coombs)
25
Signs and symptoms of PK deficiency
hemolysis, splenomegaly, gallstones aplastic crises
26
Signs and symptoms of Sickle cell anemia
Vessel damage leading to multi-organ damage (lungs, retina, spleen, kidney, CNS), priaplasm, and aplastic crisis
27
Signs and symptoms of Anemia due to renal dysfunction
``` Prolonged bleeding time, fatigue, pallor, decreased exercise tolerance, dyspnea, tachypnea ```
28
Signs and symptoms of Endocrine related anemia
``` Thyroid: Hyper or hypactivity, weight gain or loss, skin, hair nail changes, Adrenal: vomiting dehydration weakness, circulatory collapse ```
29
List the organs associated with absorption
D J I | I F B