colon part 1 Flashcards

IBD, bowel obs, celiac

1
Q

normal bowel function

constipation defintion

A

3 stools per day to 3 stools per week

constipation is a decrease in stool volume and increase in stool firmness accompanied by straining

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2
Q

describe the bowel sounds and symptoms in an obstruction

small

large

A

hight pitched and comes in rushes

small: abd pain, distention, vomiting partially digested food, obstipation
large: distention and pain

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3
Q

sx of volvulus

A

cramping abdominal pain and distention(rigid), nausea, vomiting, and obstipation

maybe signs of shock

abdominal tymphany, tachycardia, fever, severe pain with ischemia

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4
Q

how to dx volvulus

A

abdominal plain film which shows colonic distention

CT with oral contrast

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5
Q

how to dx malabsorption

sx

A

72 hr fecal fat test; d-xylose test

diarrhea, bloating, abdominal discomfort;

may have wt loss, steatorrhea, edema

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6
Q

what if a fecal fat test if nml in malabsorption

A

think pancreatic insufficiency and abnormal bile salt metabolism

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7
Q

what is a D-xylose test for

A

to distinguish maldigestion(pancreatic insufficiency, bile salt deficiency) from malabsorption

nml rules out malabsorption

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8
Q

pt older than 50 y/o with new onset constipation

A

evaluate for colon cancer

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9
Q

constipation treatment

A

increase fiber to 10-20 gm/day and

fluid intake to (1.5-2L/day)

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10
Q

small and large bowel obstructions common causes

A

small: adhesion or hernias
large: neoplasm

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11
Q

test to look for a bowel obstruction

A

initial: upright radiograph may illustrate air-fluid levels and multiple dilated loops of bowel
definitive: CT abdomen

CBC: leukocytosis if there is ischemia or necrosis

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12
Q

bowel obstruction tx

  • initial tx
  • partial obstruction
  • emergency
A
  • NPO, NG suctioning, IV fluids, monitoring
  • IV hydration, NG decompression
  • if a mechanical obstruction is suspected, especially large bowel
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13
Q

volvulus defintion

common area

A

twisting of bowel, commonly in sigmoid or cecal area of the bowel, emergent!

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14
Q

volvulus tx

A

endoscopic decompression

or surgery

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15
Q

abdominal tymphany, tachycardia, fever, severe pain with ischemia

A

volvulus ischemia

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16
Q

digestion, absorption, impaired blood or lymph flow

A

can cause problems with malabsorption

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17
Q

fistulas, abscesses, aphthous ulcers, renal stones, predisposition to colonic cancer

A

complications of crohns

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18
Q

.what is celiac disease

common where

A

autoimmune: inflammation of the small bowel due to rxn with alpha gliadin in gluten containing foods (wheat, rye, barley)

most common in Europe and US

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19
Q

.sx of celiac disease

what about in infants and children

A

diarrhea, steatorrhea, flatulence, wt loss, weakness, abdominal distention

dermatitis herpetiformis (pruritic papulovesicular rash on extensor surfaces, neck, trunk, scalp)

kids: failure to thrive, growth delays

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20
Q

.how to dx celiac disease

A

diagnostic: small bowel biopsy (atrophy of villi)

screen with transgluaminase IgA antibodies test of choice.

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21
Q

.what part of the bowel does crohns involve

population

A

the small and large bowel, most commonly the terminal ileum and right colon. rectum is spared!!

skip areas are characteristic

smokers have signficant increased risk

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22
Q

.crohns vs UC onset

A

c: gradual; UC: gradual or sudden

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23
Q

.crohns vs UC distribution

A

C: mouth to anus, skip areas, spares rectum. UC: distal to proximal, continuous

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24
Q

.crohns vs UC depth of lesions

A

C: transmural. sometimes leading to fistulas

UC: mucosal surface

25
.crohns vs UC symptoms
C: diarrhea(non bloody) and pain. UC: bloody pus filled diarrhea(more than 6 per day is severe), tenesmus
26
.what is tenesmus
feeling that u constantly need to pass stools even though ur bowels are empty
27
.crohns vs UC complications
C: fistulas common, perianal disease, iron/B12 def, granulomas UC: toxic megacolon, primary sclerosing cholangitis, colon ca
28
.diarrhea in crohns and UC
crohns: no visible blook UC: bloody diarrhea hallmark
29
.tx for crohns ileocolonic illeal and proximal colon severe/refractory
ileocolonic: mesalamine (5-ASA) or po glucocorticoid illeal and proximal colon: glucocorticoid severe/refractory: azathioprine, methotrexate, anti TNF agents(infliximab)
30
.where does pain occur in UC
pain less common but occurs in left lower quadrant
31
.toxic megacolon and colon cancer in crohns vs UC
more likely in UC
32
scleritis, episcleritis, arthritides, sclerosing cholangitis, erythema nodosum, pyoderma gangrenosum...
complications of UC
33
crohns vs UC: smoking
smoking increases disease in crohns but protective in UC
34
barium enema for UC ok
no, can b/c of risk of perforation. do colonoscopy or sigmoidoscopy
35
.tx for UC
topical or oral aminosalicylates first line immunodulators for refractory disease surgery: total proctocolectomy
36
.tests for crohns
upper GI series initial test of choice: string sign endoscopy: cobblestoning bx will reveal transmural inflammation, noncaseating granulomas
37
increased sedimentation rate, anemia, nutritional and electrolyte imbalances during what
crohns exacerbations
38
UC starts where onset
starts distally, at the rectum, and progresses proximally disease is CONTINUOUS gradual onset but also can be abrupt
39
UC tests
anemia, increased ESR, decreased serum albumin abdominal plan film xray may show colonic dilation \*\*sigmoidoscopy or colonoscopy best method for dx avoid colonoscopy and barium edema in acute disease because of risk of perforation and toxic megacolon
40
avoid what tests in crohns and UC
Crohns: avoid contrast studies and endoscopic procedures because of possibility of inducing toxic megacolon or perforation UC: avoid colonoscopy and barium edema in acute disease because of risk of perforation and toxic megacolon
41
.best tests for crohns and UC
crohns: upper GI series with small bowel follow through UC: sigmoidoscopy or colonoscopy
42
crampy abdominal pain 4-5 minutes; vomiting typically follows pain
small bowel obstruction
43
leading cause of small bowel obstruction in kids and adults
kids: hernia adults: adhesions
44
postprandial bloating, intermittent crampy abdominal pain, loud BS, vomiting, constipation
bowel obstruction
45
dehydration and metabolic alkalosis
small bowel obstruction
46
lactic acidosis
prognostic sign in necrotic bowel
47
stepladder appearance on xray
small bowel obstruction
48
serologic screening tests (IgA antiendomsysial[EMA] and antitissue transglutaminase antibodies)
for celiac disease
49
constipation - gender - dx how - palpate stool where - kind of laxatives to give
females less than 2 BM a week LLQ osmotic and stimulant
50
abdominal tymphany tachycardia, fever, severe pain
volvulus
51
.cobblestone appearance elevated WBC
crohns
52
.labs: anti-Saccharomyces cerevisiae antibodies, iron/B12 def.
crohns
53
.string sign on upper GI series
crohns
54
.stovepipe or lead pipe sign
UC
55
.UC mild/mod/severe description
mild: 4 or less BM moderate: over 4 loose BM severe: 6 loose BM, severe pain, signs of toxicity
56
.cyclosporine, tacrolimus, -mab drugs, methotrexate, 6 mercaptopurine, azathioprine
UC and crohns meds
57
.diarrhea dermatitis herpetiformis (pruritic papulovesicular rash on extensor surfaces, neck, trunk, scalp)
celiac disease
58
.test of choice for lactose intolerance
hydrogen breath test
59
.nut allergy ____ mediated timing of exposure
IgE wait until 3 yo