Colon and Rectum, C48 P308-325 Flashcards
ANATOMY
Identify the arterial blood supply to the colon:
P308 (picture)
- Ileocolic artery
- Right colic artery
- Superior mesenteric artery (SMA)
- Middle colic artery
- Inferior mesenteric artery (IMA)
- Left colic artery
- Sigmoidal artery
- Superior hemorrhoidal artery
(superior rectal) - Middle hemorrhoidal artery
10 Inferior hemorrhoidal artery - Marginal artery of Drummond
- Meandering artery of Gonzalez
ANATOMY
What are the white lines of
Toldt?
P309
Lateral peritoneal reflections of the
ascending and descending colon
ANATOMY
What parts of the GI tract
do not have a serosa?
P309
Esophagus, middle and distal rectum
ANATOMY What are the major anatomic differences between the colon and the small bowel? P309
Colon has taeniae coli, haustra, and appendices epiploicae (fat appendages), whereas the small intestine is smooth
ANATOMY What is the blood supply to the rectum: Proximal? P309
Superior hemorrhoidal (or superior rectal) from the IMA
ANATOMY What is the blood supply to the rectum: Middle? P309
Middle hemorrhoidal (or middle rectal) from the hypogastric (internal iliac)
ANATOMY What is the blood supply to the rectum: Distal? P309
Inferior hemorrhoidal (or inferior rectal)
from the pudendal artery (a branch of
the hypogastric artery)
ANATOMY What is the venous drainage of the rectum: Proximal? P309
Via the IMV to the splenic vein, then to
the portal vein
ANATOMY What is the venous drainage of the rectum: Middle? P309
Via the iliac vein to the IVC
ANATOMY What is the venous drainage of the rectum: Distal? P309
Via the iliac vein to the IVC
COLORECTAL CARCINOMA
What is it?
P309
Adenocarcinoma of the colon or rectum
COLORECTAL CARCINOMA
What is the incidence?
P309
Most common GI cancer Second most common cancer in the United States Incidence increases with age starting at 40 and peaks at 70 to 80 years
COLORECTAL CARCINOMA
How common is it as a cause
of cancer deaths?
P309
Second most common cause of cancer
deaths
COLORECTAL CARCINOMA
What is the lifetime risk of
colorectal cancer?
P310
6%
COLORECTAL CARCINOMA
What is the male to female
ratio?
P310
≈1:1
COLORECTAL CARCINOMA
What are the risk factors?
P310
Dietary: Low-fiber, high-fat diets correlate with increased rates Genetic: Family history is important when taking history FAP, Lynch’s syndrome IBD: Ulcerative colitis > Crohn’s disease, age, previous colon cancer
COLORECTAL CARCINOMA
What is Lynch’s syndrome?
P310
HNPCC = Hereditary NonPolyposis
Colon Cancer—autosomal-dominant
inheritance of high risk for development
of colon cancer
COLORECTAL CARCINOMA What are current ACS recommendations for polyp/colorectal screening in asymptomatic patients without family (first-degree) history of colorectal cancer? P310
Starting at age 50, at least one of the following test regimens is recommended: Colonoscopy q 10 yrs Double contrast barium enema (DCBE) q 5 yrs Flex sigmoidoscopy q 5 yrs CT colonography q 5 yrs
COLORECTAL CARCINOMA What are the current recommendations for colorectal cancer screening if there is a history of colorectal cancer in a first-degree relative less than 60 years old? P310
Colonoscopy at age 40, or 10 years before
the age at diagnosis of the youngest
first-degree relative, and every 5 years
thereafter
COLORECTAL CARCINOMA What percentage of adults will have a guaiac-positive stool test? P310
≈2%
COLORECTAL CARCINOMA What percentage of patients with a guaiac-positive stool test will have colon cancer? P310
≈10%
COLORECTAL CARCINOMA What signs/symptoms are associated with the following conditions: Right-sided lesions? P311
Right side of bowel has a large luminal diameter, so a tumor may attain a large size before causing problems Microcytic anemia, occult/melena more than hematochezia PR, postprandial discomfort, fatigue
COLORECTAL CARCINOMA What signs/symptoms are associated with the following conditions: Left-sided lesions? P311
Left side of bowel has smaller lumen and semisolid contents Change in bowel habits (small-caliber stools), colicky pain, signs of obstruction, abdominal mass, heme() or gross red blood Nausea, vomiting, constipation
COLORECTAL CARCINOMA
From which site is melena
more common?
P311
Right-sided colon cancer