Appendix, C45 P293-301 Flashcards
What vessel provides blood
supply to the appendix?
P293
Appendiceal artery—branch of the
ileocolic artery
Name the mesentery of the
appendix.
P293
Mesoappendix (contains the appendiceal
artery)
How can the appendix be
located if the cecum has
been identified?
P293
Follow the taenia coli down to the
appendix; The taeniae converge on the
appendix
What is it?
P294
Inflammation of the appendix caused by obstruction of the appendiceal lumen, producing a closed loop with resultant inflammation that can lead to necrosis and perforation
What are the causes?
P294
Lymphoid hyperplasia, fecalith
(a.k.a. appendicolith)
Rare—parasite, foreign body, tumor
(e.g., carcinoid)
What is the lifetime incidence of acute appendicitis in the United States? P294
≈7%!
What is the most common
cause of emergent abdominal
surgery in the United States?
P294
Acute appendicitis
How does appendicitis
classically present?
P294
Classic chronologic order: 1. Periumbilical pain (intermittent and crampy) 2. Nausea/vomiting 3. Anorexia 4. Pain migrates to RLQ (constant and intense pain), usually in <24 hours
Why does periumbilical pain
occur?
P294
Referred pain
Why does RLQ pain occur?
P294
Peritoneal irritation
What are the signs/symptoms?
P294
Signs of peritoneal irritation may be present: guarding, muscle spasm, rebound tenderness, obturator and psoas signs, low-grade fever (high grade if perforation occurs), RLQ hyperesthesia
Define the following terms:
Obturator sign
P294
Pain upon internal rotation of the leg
with the hip and knee flexed; seen in
patients with pelvic appendicitis
Define the following terms:
Psoas sign
P295
Pain elicited by extending the hip with
the knee in full extension or by flexing
the hip against resistance; seen classically
c retrocecal appendicitis
Define the following terms:
Rovsing’s sign
P295
Palpation or rebound pressure of the
LLQ results in pain in the RLQ; seen in
appendicitis
Define the following terms:
Valentino’s sign
P295
RLQ pain/peritonitis from succus
draining down to the RLQ from a
perforated gastric or duodenal ulcer
Define the following terms:
McBurney’s point
P295 (picture)
Point one third from the anterior
superior iliac spine to the umbilicus
(often the point of maximal tenderness)
What is the differential diagnosis for:
Everyone?
P295
Meckel’s diverticulum, Crohn’s
disease, perforated ulcer, pancreatitis,
mesenteric lymphadenitis, constipation,
gastroenteritis, intussusception, volvulus,
tumors, UTI (e.g., cystitis), pyelonephritis,
torsed epiploicae, cholecystitis, cecal
tumor, diverticulitis (floppy sigmoid)
What is the differential diagnosis for:
Females?
P295
Ovarian cyst, ovarian torsion, tuboovarian
abscess, mittelschmerz, pelvic inflammatory
disease (PID), ectopic pregnancy,
ruptured pregnancy
What lab tests should be
performed?
P296
CBC: increased WBC (>10,000 per mm
in >90% of cases), most often with a
“left shift”
Urinalysis: to evaluate for pyelonephritis
or renal calculus
Can you have an abnormal
urinalysis with appendicitis?
P296
Yes; mild hematuria and pyuria are
common in appendicitis with pelvic
inflammation, resulting in inflammation
of the ureter
Does a positive urinalysis
rule out appendicitis?
P296
No; ureteral inflammation resulting from
the periappendiceal inflammation can
cause abnormal urinalysis
What additional tests can be
performed if the diagnosis is
not clear?
P296
Spiral CT, U/S (may see a large,
noncompressible appendix or fecalith),
AXR
In acute appendicitis, what
classically precedes vomiting?
P296
Pain (in gastroenteritis, the pain
classically follows vomiting)
What radiographic studies
are often performed?
P296
CXR: to rule out RML or RLL pneumonia, free air AXR: abdominal films are usually nonspecific, but calcified fecalith present in about 5% of cases
What are the radiographic
signs of appendicitis on AXR?
P296
Fecalith, sentinel loops, scoliosis away
from the right because of pain, mass effect
(abscess), loss of psoas shadow, loss of
preperitoneal fat stripe, and (very rarely) a
small amount of free air if perforated
With acute appendicitis, in what percentage of cases will a radiopaque fecalith be on AXR? P296
Only ≈5% of the time!
What are the CT findings
with acute appendicitis?
P296
Periappendiceal fat stranding,
appendiceal diameter >6 mm,
periappendiceal fluid, fecalith
What are the preoperative
medications/preparation?
P297
- Rehydration with IV fluids (LR)
- Preoperative antibiotics with
anaerobic coverage (appendix is
considered part of the colon)
What is a lap appy?
P297
Laparoscopic appendectomy; used in
most cases in women (can see adnexa) or
if patient has a need to quickly return to
physical activity, or is obese
What is the treatment
for nonperforated acute
appendicitis?
P297
Nonperforated—prompt appendectomy
(prevents perforation), 24 hours of
antibiotics, discharge home usually on
POD #1
What is the treatment for
perforated acute
appendicitis?
P297
Perforated—IV fluid resuscitation and prompt appendectomy; all pus is drained with postoperative antibiotics continued for 3 to 7 days; wound is left open in most cases of perforation after closing the fascia (heals by secondary intention or delayed primary closure)
How is an appendiceal
abscess that is diagnosed
preoperatively treated?
P297
Usually by percutaneous drainage of the
abscess, antibiotic administration, and
elective appendectomy ≈6 weeks later
(a.k.a. interval appendectomy)
If a normal appendix is found upon exploration, should you take out the normal appendix? P297
Yes
How long after removal of a NONRUPTURED appendix should antibiotics continue postoperatively? P297
For 24 hours
Which antibiotic is used
for NONPERFORATED
appendicitis?
P297
Anaerobic coverage: Cefoxitin®,
Cefotetan®, Unasyn®, Cipro®, and Flagyl®
What antibiotic is used for a
PERFORATED appendix?
P297
Broad-spectrum antibiotics (e.g.,
Amp/ Cipro®/Clinda or a penicillin such
as Zosyn®)
How long do you give
antibiotics for perforated
appendicitis?
P298
Until the patient has a normal WBC
count and is afebrile, ambulating, and
eating a regular diet (usually 3–7 days)
What is the risk of
perforation?
P298
≈25% by 24 hours from onset of
symptoms, ≈50% by 36 hours, and
≈75% by 48 hours
What is the most common
general surgical abdominal
emergency in pregnancy?
P298
Appendicitis (about 1/1750; appendix
may be in the RUQ because of the
enlarged uterus)
What are the possible
complications of
appendicitis?
P298
Pelvic abscess, liver abscess, free
perforation, portal pylethrombophlebitis
(very rare)
What percentage of the
population has a retrocecal,
retroperitoneal appendix?
P298
≈15%
What percentage of negative
appendectomies is
acceptable?
P298
Up to 20%; taking out some normal
appendixes is better than missing a case
of acute appendicitis that eventually
ruptures
Who is at risk of dying from
acute appendicitis?
P298
Very old and very young patients
What bacteria are associated with “mesenteric adenitis” that can closely mimic acute appendicitis? P298
Yersinia enterolytica
What is an “incidental
appendectomy”?
P298
Removal of normal appendix during
abdominal operation for different
procedure
What are complications of
an appendectomy?
P298
SBO, enterocutaneous fistula, wound
infection, infertility with perforation in
women, increased incidence of right
inguinal hernia, stump abscess
What is the most common
postoperative complication?
P298
Wound infection
CLASSIC INTRAOPERATIVE QUESTIONS What is the difference between a McBurney’s incision and a Rocky-Davis incision? P299
McBurney’s is angled down (follows ext oblique fibers), and Rocky-Davis is straight across (transverse)
CLASSIC INTRAOPERATIVE QUESTIONS What are the layers of the abdominal wall during a McBurney incision? P299
- Skin
- Subcutaneous fat
- Scarpa’s fascia
- External oblique
- Internal oblique
- Transversus muscle
- Transversalis fascia
- Preperitoneal fat
- Peritoneum
CLASSIC INTRAOPERATIVE QUESTIONS What are the steps in laparoscopic appendectomy (lap appy)? P299
- Identify the appendix
- Staple the mesoappendix (or coagulate)
- Staple and transect the appendix at
the base (or use Endoloop® and cut
between) - Remove the appendix from the
abdomen - Irrigate and aspirate until clear
CLASSIC INTRAOPERATIVE QUESTIONS Do you routinely get peritoneal cultures for acute appendicitis (nonperforated)? P299
No
CLASSIC INTRAOPERATIVE QUESTIONS How can you find the appendix after identifying the cecum? P299
Follow the taeniae down to where they
converge on the appendix
CLASSIC INTRAOPERATIVE QUESTIONS Which way should your finger sweep trying to find the appendix? P299
Lateral to medial along the lateral
peritoneum—this way you will not tear
the mesoappendix that lies medially!
CLASSIC INTRAOPERATIVE QUESTIONS How do you get to a retrocecal and retroperitoneal appendix? P299
Divide the lateral peritoneal attachments
of the cecum
CLASSIC INTRAOPERATIVE QUESTIONS Why use electrocautery on the exposed mucosa on the appendiceal stump? P299
To kill the mucosal cells so they do not
form a mucocele
CLASSIC INTRAOPERATIVE QUESTIONS If you find Crohn’s disease in the terminal ileum, will you remove the appendix? P300
Yes, if the cecal/appendiceal base is not
involved
CLASSIC INTRAOPERATIVE QUESTIONS If the appendix is normal what do you inspect intraoperatively? P300
Terminal ileum: Meckel’s diverticulum, Crohn’s disease, intussusception Gynecologic: Cysts, torsion, etc. Groin: hernia, rectus sheath hematoma, adenopathy (adenitis)
CLASSIC INTRAOPERATIVE QUESTIONS Who first described the classic history and treatment for acute appendicitis? P300
Reginald Fitz
CLASSIC INTRAOPERATIVE QUESTIONS
Who performed the first
appendectomy?
P300
Harry Hancock in 1848 (McBurney
popularized the procedure in 1880s)
CLASSIC INTRAOPERATIVE QUESTIONS
Who performed the first lap
appy?
P300
Dr. Semm (GYN) in 1983
APPENDICEAL TUMORS
What is the most common
appendiceal tumor?
P300
Carcinoid tumor
APPENDICEAL TUMORS What is the treatment of appendiceal carcinoid less than 1.5 cm? P300
Appendectomy (if not through the bowel
wall)
APPENDICEAL TUMORS What is the treatment of appendiceal carcinoid larger than 1.5 cm? P300
Right hemicolectomy
APPENDICEAL TUMORS What percentage of appendiceal carcinoids are malignant? P300
< 5%
APPENDICEAL TUMORS What is the differential diagnosis of appendiceal tumor? P300
Carcinoid, adenocarcinoma, malignant
mucoid adenocarcinoma
APPENDICEAL TUMORS What type of appendiceal tumor can cause the dreaded pseudomyxoma peritonei if the appendix ruptures? P300
Malignant mucoid adenocarcinoma
APPENDICEAL TUMORS
What is “mittelschmerz”?
P301
Pelvic pain caused by ovulation
APPENDICEAL TUMORS Should one remove the normal appendix with Crohn’s disease found intraoperatively? P301
Yes, unless the base of the appendix is
involved with Crohn’s disease, the normal
appendix should be removed to avoid
diagnostic confusion with appendicitis in
the future