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Kaplan > Collagen Vascular > Flashcards

Collagen Vascular Flashcards

1
Q

Criteria for Juvenile Rheumatoid Arthritis

A
  • onset at less than 16 years
  • arthritis in at least one joint
  • symptoms at least 6 weeks
  • paicuarticular, polyarticular or systemic disease in first 6 months
  • exclusion of other disease
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2
Q

Pauciartciular JRA

A
  • less than 4 joints of the lower extremities; no hip

- positive ANA, chronic anterior uveitis

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3
Q

Polyarticular JRA

A
  • 5+ joints
  • usually hand and wrist involvement
  • rheum nodules
  • cervical and hip
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4
Q

Systemic JRA

A
  • daily spiking fevers
  • salmon polymorphous rash
  • serosistis
  • will have pauci or polyarticular disease
  • may have negative sserology
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5
Q

Best Screening Test SLE

A

ANA

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6
Q

Most specific SLE test

A

Anti-smith

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7
Q

How to measure disease activity in SLE

A

anti-ds-DNA

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8
Q

Marker for lupus cerebritis

A

anti-ribsomal P

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9
Q

Antibodies found in neonatal SLE

A

anti-ro SSA or anti-La SSB due to maternal IgG crossing placenta

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10
Q

What is a lupus anticoagulant reflective of? What may it give a false positive for?

A
  • assd wtih APL antibodies and DVT
  • false positive for syphilis
  • can icnrease PTT
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11
Q

Complement SLE

A

-decreased CH50, C3, and C4

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12
Q

What finding in neonatal SLE typically doesnt resolve?

A

heart block (prologned PR to third degree)

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13
Q

Presentation Junveile Ankylosing Spondylitis

A
  • males
  • arhtitis usually in leg joints plus enthesitis (tendons, ligaments, fascia)
  • lateral skeletal joint like sacroiliac
  • anteriori uveitis, aortic regurge, atlanto axial subluxation
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14
Q

Labs Juvenile ankylosing spony

A
  • negative ANA and RF

- positive HLA B27

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15
Q

Positive ANA with speckled pattern means…

A

dermatomyositis (female, age 7)

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16
Q

ESR in Dermatomyositis

A

normal

17
Q

Tests Scleroderma

A
  • positive antiScl plus anticentromere antibodies

- ANA wit speckled pattern

18
Q

Non casesating granulomas in lungs

A

sarcoid

19
Q

Kawasakis when do you switch to low dose aspirin

A

afebrile for 3 days

20
Q

When should ESR/CRP normalize in kawasakis

A

2 months

21
Q

Epidemiology HSP

A
  • follows URI
  • age 2 to 8
  • males more
22
Q

Presentation HSP

A
  • low grade fever with arthalgia (serous, knees / ankles)
  • buttocks and legs (back of arms too) with pink maculopapules that blanch then ddevelop into petechia/ palpable purpura that resolve in1 to 4 weeks
  • colicky abdominal pain
23
Q

Complications HSP

A
  • intussusception

- renal vasculaitis

24
Q

Tx HSP

A
  • if any GI involvement give corticosteroids
  • renal like GN
  • -rember get UA and stool occult on all these patients

Kaplan (8 decks)

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