Cognitive disorder outline flashcards
agitation and aggression in AD
atypical antipsychotics
depression in AD
SSRI – Sertraline and Fluoxetine, or Tricyclic antidepressants.
psychosis in AD
Hallucinations – quetapine, olanzepine, risperidone; Delusions – atypical antipsychotics, haloperidol
sleep disorders and AD
sedatives and Promethazine
Tx of AD
cholinesterase inhibitors – donepezil, rivastigmine, galantamine; NMDA antagonists – memantine; Vitamin E
FTD Tx
SSRI – sertraline, paroxetine, fluvoxamine; Anti-psychotics – quetiapine, olanzepine, aripiprazole
why not cholinesterase inhibitors in FTD? Why not Bapineuzumab in FTD?
because it is mediated by 5HT and Dopamine. There are no B amyloid plaques.
LBD Tx
cholinesterase inhibitors, atypical antipsychotics, anti-parkinson drugs. REM sleep disorders – clonazepam and quetiapine
Vascular dementia Tx
Antihypertensives – diuretics, ACEinhibitors, B-blockers. Diabetic Mgt. Statins – simvastatin, pravastatin. Antiplatelets – aspirin, clopidogrel. Ca channel blockers – nifedipine, nimodipine
HIV dementia Tx
RT inhibitors – Dedanosine, stavudine, Zalcitabine; Rifampin; Rifabutin if MAC is present; Methylphenidate
drug induced amnesia
Midazolam, Flunitrazepam, Rohypnol
anterograde amnesia
cannot remember anything new
retrograde amnesia
cannot remember prior to point in time
global amnesia
no ability to form new or recall old memories
transient amnesia
post trauma
