coagulopathy

Question 1

What are the two phases of DIC

Answer 1

1. hypercoagulable- form widepsread thromboses & organ dysfunction
2. consumption phase- widespread bleeding

Question 2

Why can pancreatitis cause DIC?

Answer 2

trypsin released- activate coagulation factors

Question 3

What is the term to describe seeing shistocytes, spherocytes, keratocytes, and acanthocytes in DIC in the blood?

Answer 3

microangiopathic hemolytic anemia

Question 4

flying in DIC formation

Answer 4

thrombocytopenia

anemia (fragmentation hemolysis)

schistocytes, acanthocytes, keratocytes, low # spherocytes

decreased fibrinogen

hemostatic tests depend on phase

increased FDP

decreased AT3

Question 5

What test could you use to detect DIC early?

Answer 5

TEG

Question 6

What two toxins can cause vit K antagonism/def?

Answer 6

rodenticides (warfarin, brodifacoum, bromadiolone)

moldy sweet clover (dicumarol)

Question 7

When do we consider an dog symptomatic for vWD?

Answer 7

<35% conc. vWF

Question 8

What are the types of vWD?

Answer 8

Type 1- all multimers but decreased (doberman_

Type 2- largest multimer def (german pointer)

Type 3- def in all multimers (ST, shelties, CBR, DK)

Question 9

diagnostic findings of vWD?

Answer 9

prolong BMBT

platelet type bleeding

normal platelet count

PTT prolong in horses but not dogs

PT normal