COAGULATIONSYSTEMDISORDER Flashcards
1
Q
1. The APTT is sensitive to a deficiency of which clotting factor? A. Factor VII B. Factor X C. PF3 D. Calcium
A
B
2
Q
2. Which test result would be normal in a patient with dysfibrinogenemia? A. Thrombin time B. APTT C. PT D. Immunologic fibrinogen level
A
d
3
Q
3. A patient with a prolonged PT is given intravenous vitamin K. The PT corrects to normal after 24 hours. What clinical condition most likely caused these results? A. Necrotic liver disease B. Factor X deficiency C. Fibrinogen deficiency D. Obstructive jaundice
A
d
4
Q
4. Which factor deficiency is associated with a prolonged PT and APTT? A. X B. VIII C. IX D. XI
A
a
5
Q
- A prolonged APTT is corrected with factor
VIII– deficient plasma but not with factor
IX–deficient plasma. Which factor is deficient?
A. V
B. VIII
C. IX
D. X
A
c
6
Q
6. Which of the following is a characteristic of classic hemophilia A? A. Prolonged bleeding time B. Autosomal recessive inheritance C. Mild to severe bleeding episodes D. Prolonged PT
A
c
7
Q
7. Refer to the following results: PT = prolonged APTT = prolonged Platelet count = decreased Which disorder may be indicated? A. Factor VIII deficiency B. von Willebrand’s disease C. DIC D. Factor IX deficiency
A
c
8
Q
- Which of the following is a predisposing condition for the development of DIC?
A. Adenocarcinoma
B. Idiopathic thrombocytopenic purpura (ITP)
C. Post-transfusion purpura (PTP)
D. Heparin-induced thrombocytopenia (HIT)
A
a
9
Q
9. Factor XII deficiency is associated with: A. Bleeding episodes B. Epistaxis C. Decreased risk of thrombosis D. Increased risk of thrombosis
A
d
10
Q
10. The following results were obtained on a patient: normal platelet count and function, normal PT, and prolonged APTT. Which of the following disorders is most consistent with these results? A. Hemophilia A B. Bernard–Soulier syndrome C. von Willebrand’s disease D. Glanzmann’s thrombasthenia
A
a
11
Q
11. The following laboratory results were obtained from a 40-year-old woman: PT = 20 sec; APTT =50 sec; thrombin time = 18 sec. What is the most probable diagnosis? A. Factor VII deficiency B. Factor VIII deficiency C. Factor X deficiency D. Hypofibrinogenemia
A
D
12
Q
- When performing a factor VIII activity assay, a patient’s plasma is mixed with:
A. Normal patient’s plasma
B. Factor VIII deficient plasma
C. Plasma with a high concentration of factor VIII
D. Normal control plasma
A
b
13
Q
13. The most suitable product for treatment of factor VIII deficiency is: A. Fresh frozen plasma B. Factor VIII concentrate C. Prothrombin complex concentrate D. Factor V Leiden
A
b
14
Q
14. Which of the following is associated with an abnormal platelet aggregation test? A. Factor VIII deficiency B. Factor VIII inhibitor C. Lupus anticoagulant D. Afibrinogenemia
A
d
15
Q
15. Refer to the following results: PT = normal APTT = prolonged Bleeding time= increased Platelet count = normal Platelet aggregation to ristocetin = abnormal Which of the following disorders may be indicated? A. Factor VIII deficiency B. DIC C. von Willebrand’s disease D. Factor IX deficiency
A
C
