coagulation tests

Question 1

what does aPTT measure?

Answer 1

1. measures integrity of

• intrinsic pathway
  ( 12, 11, 8 , 9 )
• common clotting pathway

Question 2

what does Prothrombin time measure?

Answer 2

1. measures integrity of
   - extrinsic pathway
   - common pathway

Question 3

extrinsic pathway : coagulation factors

Answer 3

1. Factor 7

2. common : 10, 2 , 1

Question 4

intrinsic pathways : coagulation factors

Answer 4

1. 12, 11, 9 8

2. common : 10, 2 1

Question 5

Prolonged PT and APTT

Answer 5

1. common pathway factors affected only

2 , 5 , 10, 1 and 2

Question 6

common pathway : coagulation factors

Answer 6

2 , 5 , 10, 1 and 2

Question 7

Name 3 causes of prolonged APTT?

Answer 7

1. Von Willebrand disease
2. DIC
3. Heparin therapy
4. Haemophilia A / B

Question 8

Name 3 causes PT time?

Answer 8

1. Liver disease
2. Warfarin therapy - ( factor 2, 9, 9 and 10 are vitamin K depedant)
3. DIC
4. Vitamin K deficiency