coag

Question 1

FIbrin is also known as what factor?

Answer 1

II

Question 2

Thrombin is also known as what factor?

Answer 2

I

Question 3

What Factors are involved in the Intrinsic pathway in order?

Answer 3

XII
XI
IX
X
(active form of each activating the next)

Question 4

What is the ultimate goal of coag?

Answer 4

Fibrin

Question 5

What is the inactive form of factor I?

Answer 5

Fibrinogen

Question 6

What do both intrinsic and extrinsic pathways converge onto?

Answer 6

Activated X

Question 7

What factors are involved in the extrinsic pathway?

Answer 7

III (tissue factor)
VII
X

Question 8

Which pathway gets activated by the original insult?

Answer 8

Extrinsic

Question 9

Which pathway gets most of the coagulation done?

Answer 9

Intrinsic

Question 10

How does the pathway work?

Answer 10

Tissue factor activates VII which activates X
X activates a little bit of thrombin
Thrombin gets the intrinsic “work horse” going

Question 11

What factors does thrombin activate?

Answer 11

5,7,8,11,13

Question 12

What does factor XIII do?

Answer 12

Cross-links fibrin!

Question 13

If you remove one of the factors, the person can still clot pretty well, which one is it?

Answer 13

XII

Question 14

Where does factor VIII come in?

Answer 14

Helps Factor IX

Question 15

Where does factor V come in?

Answer 15

Helps factor X

Question 16

What does plasmin do?

Answer 16

breaks apart fibrin meshwork

Question 17

What stimulates the production of antithrombin?

Answer 17

Thrombin

Question 18

What does antithrombin do?

Answer 18

Decrease amount of thrombin being produced from prothrombin

Question 19

What do you call it when a person can’t clot well?

Answer 19

Hemophilia

Question 20

What are the 3 types of Hemophilia?

Answer 20

A: Factor VIII
B: Factor IX
C: Factor XI

Question 21

The hemophilias all come from which pathway?

Answer 21

Intrinsic