CNS tumors Flashcards
How does the location of adult CNS tumors differ from the location of child CNS tumors?
adult tumors are usually above the tentorium cerebelli
child tumors are usually below the tentorium cerebelli
What are the most common CNS tumors in adults? Which ones are malignant? which ones are benign?
meningioma, glioblastoma multiforme, schwannoma, oligodendroglioma
malignant - glioblastoma multiforme, oligodendroglioma
benign - meningioma, schwannoma
What are the most common CNS tumors in children? Which ones are malignant? Which ones are benign?
ependymoma, pilocytic astrocytoma, medulloblastoma, craniopharyngioma
malignant - ependymoma, medulloblastoma
benign - pilocytic astrocytoma, craniopharyngioma
Which CNS tumor is characterized by a “butterfly lesion” where the tumor crosses the corpus callosum?
glioblastoma multiforme
Which CNS tumor is characterized by a whorled pattern and psamomma bodies on histology?
meningioma
Which CNS tumor usually compresses CN VIII at the cerebellopontine angle? How does it present?
schwannoma. Presents as loss of hearing and tinnitus
Which CNS tumor has a “fried egg” appearance on histology?
oligodendroglioma
Which CNS tumor is a benign tumor of astrocytes? Which CNS tumor is a malignant tumor of astrocytes?
benign - pilocytic astrocytoma
malignant - glioblastoma multiforme
Where does a pilocytic astrocytoma usually arise?
the cerebellum
Which CNS tumor arises from neuroectoderm cells in the cerebellum?
medulloblastoma
Which CNS tumor arises in the 4th ventricle and causes hydrocephalus?
ependymoma
Which CNS tumor arises from epithelial remnants of Rathke’s pouch and can show “tooth-like” tissue on imaging?
craniopharyngioma
Which CNS tumor is characterized by regions of necrosis surrounded by tumor cells (i.e. pseudopalisading cells)?
glioblastoma multiforme
Which CNS tumor is characterized by a proliferation of arachnoid cells?
meningioma
Which CNS tumor is positive for S-100 on immunostaining?
Schwannoma
