CNS II Test

Question 1

Carter is a 15-year-old boy. Lately, he has been missing school for stomach aches and headaches. He has trouble sleeping and has been avoiding extracurricular activities. His test scores have dropped in school, and he says he is having trouble concentrating during exams. These signs and symptoms are consistent with:
anxiety
manic/depressive disorder
Pick’s disease
obsessive-compulsive disorder

Answer 1

anxiety

Question 2

Tricyclic antidepressants:
are primarily dopamine agonists
are favored for the fact that they have few adverse effects or drug interactions
are first line treatment for major depression
affect both serotonergic and norepinephrine neurotransmission

Answer 2

affect both serotonergic and norepinephrine neurotransmission

Question 3

Which of the following symptoms is/are most consistent with major depressive disorder?
high risk behaviours
ritualistic compulsions
restlessness, difficulty concentrating
sleeping excessively

Answer 3

sleeping excessively

Question 4

Ms. R. is a 23 year old female. She works in a retail shop. Before she leaves her apartment each morning, she washes her breakfast dishes in the same order each day, wiping each item 51 times clockwise and places them in the cupboard aligned in a specific way. She brushes her hair 51 strokes while whistling “Happy Birthday” every morning and every evening. If her phone gives her a notification, she knocks wood three times and pokes her forehead. She washes her hands after touching any object in the kitchen or bathroom, which interrupts the routine. Ms. R. has to start her day 3 hours before her work shift to make it to work on time.
What is the first-line therapy for this condition?
electroconvulsive therapy
SSRIs
atypical antipsychotic drugs
benzodiazepines

Answer 4

SSRIs

Question 5

Which of the following is correct regarding major depression?
Treatment with medications is approximately 80% effective
Men are more susceptible to depression than women.
Counselling and medication is associated with the best outcomes
Depression affects at least 25% of the population, globally

Answer 5

Counselling and medication is associated with the best outcomes

Question 6

Serotonin reuptake inhibitors mechanism of action includes:
inhibition of postsynaptic dopamine receptors
upregulation of SERT
inhibition of the presynaptic serotonin uptake transporter
inhibition of monoamine oxidase, which metabolizes serotonin
direct agonist of serotonin receptors in the postsynaptic membrane

Answer 6

inhibition of the presynaptic serotonin uptake transporter

Question 7

Which of the following is a potential symptom of major depression?
fatigue
grandiose thinking
tachycardia and sweating
auditory hallucinations

Answer 7

fatigue