CNS Flashcards
Meningiomas over represented in these 3 dog breeds?
Golden retrievers
Boxers
Miniature schnauzers
What is the median survival time for cats with surgically resected meningiomas?
23-28 months
Gliomas over represented in these 3 dog breeds?
Boxers
Boston terriers
Bulldogs
Choroid plexus tumors over represented in which dog breed?
Golden retrievers
What two histopath subtypes are included in gliomas?
Astrocytomas and oligodendrogliomas
Most meningiomas arise from the ——layer?
Arachnoid
Which of the following have been associated with a negative prognosis in dogs with cerebral meningiomas?
i. histologic subtype (anaplastic and fibroblastic) ii. increased VEGF expression iii. increased Ki-67 iv. grade as described in the human literature v. increased progesterone receptor expression
a. i, ii, iii
b. ii, iii, iv
c. iii, iv, v
d. i, ii, iv
e. ii, iii, v
d.
progesterone receptor expression was INVERSELY related to PCNA; therefore, increased progesterone would have decreased PCNA and better survival
A 12-year-old, male castrated, Labrador retriever has been diagnosed with multifocal forebrain masses. What is the most likely neoplastic diagnosis for these masses?
a. metastatic hemangiosarcoma b. metastatic transitional cell carcinoma c. lymphoma d. meningioma e. glioma
a.
Multifocal masses are most likely to be metastatic disease and the most common is metastatic hemangiosarcoma
A 7 year-old, spayed female mixed breed dog is imaged and finds a 4-cm, pedunculated, uniformly contrast-enhancing mass within the lateral ventricle. There is another mass noted at the obex that is similarly contrast enhancing. What is the MOST likely diagnosis for these findings?
a. glioma b. choroid plexus carcinoma c. anaplastic meningioma d. microcytic meningioma e. neuroblastoma
b.
What is the accuracy for MRI in evaluating for tumor type?
a. 50% b. 60% c. 70% d. 80% e. 90%
c.
The incidence of current, unrelated neoplasia in patients diagnosed with intracranial neoplasia is:
a.
c.
A 12-year-old, spayed female, domestic shorthair is diagnosed with an extraaxial cerebral tumor most consistent with meningioma. The cat undergoes surgery and removes the tumor. The median survival time for this cat is:
a. 3 months b. 6 months c. 12 months d. 18 months e. 24 months
e.
Which of the following are CORRECTLY paired with the most common spinal tumors?
i. primary: dog: meningioma ii. secondary: cat: lymphoma iii. primary: dog: nephroblastoma iv. secondary: cat: osteosarcoma v. primary: cat: lymphoma vi. secondary: dog: carcinoma
a. i, ii, v, vi
b. ii, iii, v, vi
c. i, iv, v
d. ii, iii, v
e. iii, iv, vi
c.
Spinal cord nephroblastomas are MOST common in which of the following breeds?
a. Dachshunds and Rhodesian Ridgeback b. Great Dane and Golden Retriever c. German Shepherd and Boston Terrier d. Golden Retriever and German Shepherd e. Great Dane and Rhodesian Ridgeback
d.
What percentage of cats diagnosed with spinal lymphoma have extraneural evidence of lymphoma?
a. 25% b. 55% c. 65% d. 85% e. 95%
d.