Clotting and Blood Transfusions Flashcards
PeT Brad PiTT
pt - extrinsic
ptt - intrinsic
clotting cascade - what happens first?
venoconstriction
clotting: after venoconstriction, _____tells platelets to do what?
vWF (8) tells platelets to stick to the open wound
clotting: after VFW directs platelets, what happens?
platelets call for backup platelets and fibrin
clotting: platelets call for backup, what does fibrin do?
fibrin strenghthens clot
when the clot is done, what happens
fibrinolysis
what electrolyte is pertinent in lots of clotting factor conversions?
Calcium - Cheeseheads convert plays
Vitamin K dependent factors
2, 7, 9, 10
vWF is best frans with what factor?
8 Dobermans
99% of cats are type what?
A. type A. assholes
Type B cats - three breeds
the ugly ones - cornish, abyssinian, devon rex
Siamese, tonkinese, burmese and russian blue cats will never be type what?
B – never B
Universal canine donor
1.1 negative
Blood transfusion rates initially
1ml/kg/hr
ionized calcium is factor # what? (iconic cheesehead)
4
extrinsic pathway is initiated by what type of trauma?
tissue trauma
Extrinsic is nice and short - what two factors before X?
Lucky #7 – then 9 and 10
when do D-dimers come into play?
clot breakdown
Factor X marks the spot of the common pathway. What factor likes to snuggle in with factor X?
Factor V
PT tests what pathways (and factors?)
Extrinsic AND Common
Ext - 7, 9,
Common - $10, $5, $2, $1
Dolla dolla bills, yo.
What factors make up the common pathway?
$10
$5
$2
$1
Prothrombin is PRO but he sits on the bench. What factor?
Factor 2
Fibrinogen is #1!!
Fibrinogen is factor 1
Brad PiTT is the tenet of movies and TV. What factors are the intrinsic pathway?
Twelve Eleven Nine Eight Ten
PTT tests what pathway (and factors)
Intrinsic
TENET (twelve, eleven, nine, eight, ten)
Common - $10, $5, $2, $1
Delayed transfusion reaction - how long and what happens?
7-10 days - rbcs are eaten up and thrown away
How can improper handling of blood products cause an issue when transfused?
giving hemolyzed blood - can cause fever or DIC (OVER PROTECTION)
Frozen plasma has everything FFP has except what two factors?
5 and 8
Besides clotting factors, FFP and FP have what two other things?
Albumin
vWf
Aminocaproic Acid is used for what?
slow the breakdown of clots – vWf patients