Clopidogrel

Question 1

What is Clopidogrel’s brand name?

Answer 1

Plavix

Question 2

What is Clopidogrel’s therapeutic category?

Answer 2

Antiplatelet agent, thienopyridine

Question 3

What are Clopidogrel’s indications?

Answer 3

Arterial thrombosis folling myocardial infarction or stroke

Question 4

What is Clopidogrel’s usual adult dose?

Answer 4

75mg once daily

May use loading dose of 300-600mg in specific occasions

Question 5

What are Clopidogrel’s side effects?

Answer 5

Bleeding, bruising, rash

Question 6

What are Clopidogrel’s monitoring parameters?

Answer 6

Bleeding

Hgb and HCT

Question 7

What are Clopidogrel’s available dosage forms?

Answer 7

Oral tablet: 75mg, 300mg

Question 8

What are Clopidogrel’s warnings?

Answer 8

BLACK BOX warning: Higher rates of cardiovascular events following myocardial infarction or stent thrombosis in patients that have reduced conversion of clopidogrel to active thiol metabolite

Question 9

What are Clopidogrel’s counseling points?

Answer 9

Report unusual bleeding, dark or bloody urine or stools
Stop 5-7 days before surgical procedures if advised by healthcare professional
Avoid using with proton pump inhibitors