[CLMD] Seizures and Syncope [Hon] Flashcards

1
Q

What is a paroxysmal disorder?

What falls under this category?

A

Episodic

Migraine, syncope, dizziness, seizure, transient global amnesia

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2
Q

Define Epilepsy

A

Epilepsy is 2 or more unprovoked seizures

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3
Q

What is a consideration physicians must make with epileptic patients in terms of stigma?

A

Must be compassionate toward patients with epilepsy

HUGE stigma and restrictions towards patients w/ epilepsy

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4
Q

If you have a patient with SUSPECTED epilepsy, and the single EEG comes back negative, can you rule out epilepsy?

A

NOOOOOO

Must perform multiple EEGs to confirm

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5
Q

What is the single most important information regarding the diagnosis of epilepsy?

A

HISTORY of the events; preferably by the witnesses

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6
Q

What are the two categories of seizures?

A

Partial Seizures

Generalized Seizures

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7
Q

What is a partial:

SIMPLE seizure?

A

Focal motor or sensory activity

No loss of consciousness

Lasts seconds

NO post-ictal state

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8
Q

What is a partial:

COMPLEX seizure?

A

Nonresponsive staring

Loss of consciousness

Lasts 1-3 min

Post-ictal state

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9
Q

What is a partial:

SECONDARY generalized seizure?

A

Bilateral tonic-clonic activity

Loss of consiousness

Lasts 1-3 min

Post ictal state

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10
Q

Take home message about partial seizures:

What is the ONE form of partial seizures that does not have loss of consciousness?

A

Simple

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11
Q

What is generalized:

Absence seizure?

A

Nonresponsive staring

Rapid blinking/chewing

Loss of consciousness

No post ictal state

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12
Q

What is generalized:

Tonic-clonic seizure?

A

Bilateral extension followed by symetrical jerking of extremities

Loss of consciousness

Post ictal state

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13
Q

What is generalized:

Atonic seizure?

A

Sudden loss of muscle tone

Head drops

Patient collapses

Loss of consciousness

Post ictal state

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14
Q

What is generalized:

Myoclonic seizure?

A

Brief, rapid symmetrical jerking of extremities and or torso

Loss of consciousness

Lasts few seconds

Slight post-ictal state

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15
Q

Which of the generalized seizures has NO post ictal state?

A

Absence

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16
Q

What are the (6) antiepileptic drugs that can be used for BOTH partial and generalized seizures?

A

Valproic acid

Lamotrigine

Topiramate

Levetiracetam

Zonisamide

Perampanel

17
Q

What is the ONE drug that works for ONLY absence seizures?

A

Ethosuxamide

18
Q

What is the one combination that is synergistic in treatment of epilepsy?

A

Valproic acid

+

Lamotrigine

19
Q

What is status epilepticus?

A

Prolonged seizure (generally greater than 10 min) or repeated seizures without recovery in between

20
Q

What is the first line treatment for status epilepticus?

A

Lorazepam IV

then

Fosphenytoin/Phenobarbital/Valproic acid

21
Q

What is transient global amnesia?

A

Sudden, temporary, isolated episode of loss of memory

No other neurologic symptoms or signs

Usually lasts a few hours then resolves, usually doesn’t recur