CLL

Question 0

Cll Cytogenetics

Answer 0

13q deletion (good--opposite of myeloma)
Trisomy 12 intermediate
11q poor
17p deletion VERY POOR

Question 1

Cll immunophenotype

Answer 1

CD 19 +
CD 20+
CD 5+
CD 23+ (mantle is 23 negative)
CD 10 -

Question 2

Cll prognosis:
Zap 70
CD 38
If variable heavy chain

Answer 2

poor:
Zap 70 positive 
CD 38 positive
CD 49 positive
Ig variable heavy chain (IgV) UNMUTATED