Clinical Trials

Question 1

Power of a study

Answer 1

Probability it would detect a statistically significant difference if one exists

Question 2

Significance of a trial

Answer 2

Probability of getting the results if null hypothesis is true

Question 3

What is the main measured focus of a trial

Answer 3

Primary end point

Question 4

Kaplan Meier plot

Answer 4

Survival plot which calculates the survival rate when an end event occurs

Question 5

Hazard ratio

Answer 5

Ration of a chance of an event in one group divided by chance of the same event in another group

Question 6

What does a hazard ratio of 1, 2, and 0.5 mean

Answer 6

1 - risk same in both groups
2 - risk in first group twice as high as in second group
0.5 - risk in first group half that of second group

Question 7

Confidence interval

Answer 7

Range of values within which we are fairly confident the true population value lies

Question 8

What is the universal grading system for adverse events

Answer 8

Common Terminology Criteria for Adverse Events

Question 9

What are adverse events scored between using the CTCAE

Answer 9

1-5
5 = death