Clinical Trial Research Design

Question 1

Key features of RCT

Answer 1

Independent/dependent variables, variance, group, intervention, observation, assessment

Question 2

Variance

Answer 2

Measure of dispersion of the data
Narrow/broad

Question 3

Primary variance

Answer 3

Effect

Question 4

Secondary variance

Answer 4

Bias

Question 5

Error variance

Answer 5

Noise, random error

Question 6

Benefit of control group

Answer 6

Find effect of the experiment intervention
Causation
Primary variants

Question 7

Benefit of random assignment

Answer 7

Even groups on important characteristics
Secondary variants

Question 8

Benefit of subjects blinded to group assignment

Answer 8

Minimize changes in behavior of subjects that could effect outcome

Question 9

Benefit of testers are blinded

Answer 9

Minimize changes in tester behavior

Question 10

Benefit of testing carefully

Answer 10

Consistency of measures and treatments
Minimize noise

Question 11

Benefit of stable environmental conditions

Answer 11

Reduce secondary variants confounded
Not influenced by outside factors

Question 12

Benefit of sufficient follow ups

Answer 12

Adequate time developed
Sustained over time