Clinical Sciences Flashcards
Supply nerves tricep / bicep
C7 tricep, C6 Bicep
What shift the oxygen dissociation curve to the right?
carbon dioxide retention Increased 2,3 BG Lower pH Increased H+ ions in bloods Hyperthermia Basically anything that makes blood more acidic
25 year old blood volume
75ml/kg
Genotypes in alpha 1 anti-trypsin
M is normal gene so MM normal phenotype lung -> emphysema liver -> cirrhosis SERPINA1 gene Cigarette smoking accelerates damage A1AT normally functions to protect lung from neutrophil elastase MZ -> one z allele mosre likely to cause liver disease SZ -> compound heterozygote, more likely to develop both lung and liver complications II -> increased risk of liver disease ZZ -> increased risk of lung disease
Primary function of peroxisomes
Oxidation of branched chain fatty acids
Distal vs proximal median nerve injury
If sensation over thenar eminence is preserved, it’s distal
Types of transplant rejection
Subclinical rejection: histological changes consistent with rejection but without a rise in serum creatinine
osmosis
from low conc to high conc through semipermeable membrane
Th2 cells produce which interleukin?
IL-4
Cytokines function
Antibody isotypes
Antibody structures
Chi squared test
comparing binary outcomes
Difference pearson and spearman correlation coefficient
Pearson: looks for an association
Spearman: looks for strength of association
Where does RNA splicing occur?
In the nucleus