Clinical Sciences Flashcards

1
Q

Supply nerves tricep / bicep

A

C7 tricep, C6 Bicep

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2
Q

What shift the oxygen dissociation curve to the right?

A

carbon dioxide retention Increased 2,3 BG Lower pH Increased H+ ions in bloods Hyperthermia Basically anything that makes blood more acidic

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3
Q

25 year old blood volume

A

75ml/kg

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4
Q

Genotypes in alpha 1 anti-trypsin

A

M is normal gene so MM normal phenotype lung -> emphysema liver -> cirrhosis SERPINA1 gene Cigarette smoking accelerates damage A1AT normally functions to protect lung from neutrophil elastase MZ -> one z allele mosre likely to cause liver disease SZ -> compound heterozygote, more likely to develop both lung and liver complications II -> increased risk of liver disease ZZ -> increased risk of lung disease

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5
Q

Primary function of peroxisomes

A

Oxidation of branched chain fatty acids

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6
Q

Distal vs proximal median nerve injury

A

If sensation over thenar eminence is preserved, it’s distal

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7
Q

Types of transplant rejection

A

Subclinical rejection: histological changes consistent with rejection but without a rise in serum creatinine

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8
Q

osmosis

A

from low conc to high conc through semipermeable membrane

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9
Q

Th2 cells produce which interleukin?

A

IL-4

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10
Q

Cytokines function

A
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11
Q

Antibody isotypes

A
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12
Q

Antibody structures

A
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13
Q

Chi squared test

A

comparing binary outcomes

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14
Q

Difference pearson and spearman correlation coefficient

A

Pearson: looks for an association

Spearman: looks for strength of association

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15
Q

Where does RNA splicing occur?

A

In the nucleus

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16
Q

Endoplasmic reticulum function

A

rough ER -> protein synthesis and studied with ribosomes. Golgi body sorts these proteins.

smooth ER -> no ribosomes, function in lipid and steroid synthesis

17
Q

Which receptors allow entry of the HIV virus?

A