Clinical Outcomes

Question 1

ROC curve

Answer 1

Can help to visualize the sensitivity and specifity among a population (Golden standard, by doing additional tests or follow-ups)

Question 2

Sensitivity

Answer 2

Able to pick up disease (postive/positive+negative)

Question 3

Specificity

Answer 3

Able to exclude non-disease (false negative/false negative+false positive)

Question 4

Cohort study

Answer 4

Retrospective
No control group
No randomization
No intervention/manipulation

Question 5

RCT study

Answer 5

Prospective
Randomized
Intervention vs. controlgroup

Question 6

Case control stidu

Answer 6

Retrospective
Matching controls
Stuiable as pilot for CE study (short term)

Question 7

Systematic review

Answer 7

Explicit question

Literature search

Question 8

Meta-analysis

Answer 8

Numeric combination of study results

Review of RCTs best clinical evidence

Question 9

Validity

Answer 9

Average or tendency gives an answer which is right on the truth.
Can be influenced by bias
Systematic error