clinical neurology 161-190 Flashcards
status epilepticus A. adrenocorticotropic hormone (ACTH) B. ethosuximide C. lorazepam D. Tegretol E. valproic acid
C. lorazepam
absence seizures A. adrenocorticotropic hormone (ACTH) B. ethosuximide C. lorazepam D. Tegretol E. valproic acid
B. ethosuximide
complex partial seizures A. adrenocorticotropic hormone (ACTH) B. ethosuximide C. lorazepam D. Tegretol E. valproic acid
D . Tegretol
or
E. valproic acid
infantile seizures A. adrenocorticotropic hormone (ACTH) B. ethosuximide C. lorazepam D. Tegretol E. valproic acid
A. adrenocorticotropic hormone (ACTH)
atypical petit ma1 syndrome of Lennox-Gastaut A. adrenocorticotropic hormone (ACTH) B. ethosuximide C. lorazepam D. Tegretol E. valproic acid
E. valproic acid
Each of the following is true of polymyositis associated with carcinoma except
A. Carcinoma affects 9% of patients with polymyositis.
B. It is most commonly associated with lung and prostate cancer in men.
C. It is usually painful.
D. Muscle biopsies show no evidence of tumor cells
.E. Proximal muscles are initially affected more than distal ones.
C. It is usually painful.
V&A pp. 1484-1487. Pain with polymyositis occurs in only 15% of patientsand often suggests an additional disorder (e.g., rheumatoid arthritis).
Which of the following is least suggestive of cluster headaches?
A. associated with lacrimation and rhinorrhea
B. bilateral location
C. daily occurrence for 2 months
D. male predominance
E. orbital location
B. bilateral location
V&A p. 189. Cluster headaches typically are recurrent for 6 to 12 weeks in aunilateral orbital location. The male to female ratio is 4.5:l to 6.7:l.Lacrimation, rhinorrhea, flushing of the face, and other such parasympathetic-type responses often accompany the headache.
Organophosphate poisoning is characterized by all of the following except A. bronchial spasms B. dry mouth C. miosis D. sweating E. vomiting
B. dry mouth
V&A p. 1281. The anticholinesterase effect of organophosphate poisoningresults in increased salivation.
One of the cerebral biochemical defects in Huntington's disease is A. decreased dopamine B. decreased GABA. C.decreased norepinephrine D. decreased somatostatin E. increased acetylcholine
B. decreased GABA.
V&A p. 1125. Decreased glutamic acid decarboxylase (hence y-aminobutyricacid [GABA]) and choline acetyltransferase (hence acetylcholine) have beenfound in the striatum and lateral pallidum in Huntington’s disease. Alsoreported has been increased norepinephrine and somatostatin in the striaturn.An excess of dopamine or an increased sensitivity of striatal dopaminereceptors has been postulated in the pathogenesis of Huntington’s disease.
Prosopagnosia is associated with lesions of the
A. anterior corpus callosum
B. bilateral anterorinferior temporal lobes
C. bilateral medial temporo-occipital lobes
D. occipital poles
E. posterior corpus callosum
C. bilateral medial temporo-occipital lobes
V&A pp. 490-492. Prosopagnosia refers to the inability to identify a familiarface while retaining the ability to identify its features.
A lesion of the supplementary motor cortex produces A. echolalia B. palilalia C. poverty of spontaneous speech D. receptive aphasia E. no speech abnormalities
C. poverty of spontaneous speech
Carp p. 424.
Lesions of b e peroneal nerve produce weakness of the
A. abductor hallucis and gastrocnemius
B. extensor digitorum longus and brevis and abductor hallucis
C. gastrocnemius and flexor hallucis longus
D. tibialis anterior and extensor digitorum longus and brevis
E. tibialis anterior and flexor digitorum brevis
D. tibialis anterior and extensor digitorum longus and brevis
Which of the following is not characteristic of Tay-Sachs disease? A. abnormal startle response B. autosomal recessive inheritance C cherry-red spots in the retina D. deficiency of sphingomyelinase E. macrocephaly
D. deficiency of sphingomyelinase
V&A p. 996.*~eficienco~f hexoarninidase A characterizes Tay-Sachs disease.
Which of the following deficits is least characteristic of Alzheimer's disease? A. corticospinal tract dysfunction B. dysnomia C. Korsakoff s amnesic state D. personality change E. spatial disorientation
A. corticospinal tract dysfunction
V&A pp. 1110-1111. Corticospinal and corticosensory functions, visual acuity,and visual fields are relatively preserved throughout the course ofAlzheimer’s disease.
Each of the following is true of Guillain-Barr syndrome except
A. Disturbances of autonomic function are common.
B. High-dose steroids form the mainstay of therapy.
C. Hypo- or areflexia is characteristic
D. The mortality rate is 3%.
E. The peak severity is 10 to 14 days after onset in 80% of cases.
B.High-dose steroids form the mainstay of therapy
V&A pp. 1380-1387. Neither conventional dose nor high-dose steroids havebeen shown to be helpful in the treatment of Guillain-BarrC syndrome.