clinical drug therapy Flashcards

1
Q

the human nervous system consists of the cCNS and PNS, where does the autonomic nervous system fit in here?

A

within the PNS

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2
Q

within the PNS there are two systems- what are these and what do they mean?

A

autonomic nervous system (involuntary) and somatic nervous system (voluntary)

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3
Q

what neurotransmitters are associated with the ANS?

A

adrenergic with the sympathetic nervous system and cholinergic with the parasympathetic nervous system

so neurotransmitters norepi and acetylcholine

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4
Q

what are the 4 classes of drugs within the ANS?

A

adrenergic, anti-adrenergic, cholinergics, and anticholinergics

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5
Q

system is turned on or off with adrenergics? what kinds of drugs are used here?

A

turn ON sympathetic nervous system. use beta or alpha agonists

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6
Q

what nervous system is turned off using anti-cholinergics? what drugs are used here? way to remember it (wet or dry)

A

parasympathetic nervous system.

anticholinergics, muscarinic blockers.
dries everything up

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7
Q

what system is turned on or off when using beta or alpha blockers? what kinds of drugs are these?

A

sympathetic nervous system is turned off. anti-adrenergic

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8
Q

when you turn on the PSNS what kinds of drugs are used here? how to remember (dry or wet?)

A
  1. Turn on Para-Sympathetic Nervous System (Cholinergics)
    Muscarinics
    “Makes everything wetter”
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9
Q

Is the following statement True or False?

The two main components of the CNS are the sympathetic and parasympathetic nervous systems.

A

The two main components of the nervous system are the central and peripheral nervous systems.

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10
Q

what are the two main componenets of the nervous system?

A

central nervous system (brain and spinal cord) and peripheral nervous system

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11
Q

what are the two components of ther PNS?

A

afferent (signals from body to CNS) and efferent (from CNS to body)

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12
Q

which portion of PNS has to do with somatic and autonomic

?

A

efferent ?? assuming from slide

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13
Q

what are the protective mechanisms desiigned to help one cope with or get away from stress?

A

flight or fight

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14
Q

what is SNS stimulated by?

A

physical or emotional stress

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15
Q

intensity and duration of reponse of SNS depends on what

A

amounts of neurotransmitters present

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16
Q

what are the specific body responses of SNS?

A

Increased arterial BP and cardiac output
Increased blood flow to brain, heart, skeletal muscles
Decreased blood flow to viscera, skin, other organs not needed for fight-or-flight response
Increased blood sugar
Increased mental activity and ability to think clearly
Increased muscle strength
Increased rate of blood coagulation
Increased rate and depth of respiration
Increased sweating

17
Q

functions of the PSNS are often described as what? what does this include?

A

resting, reparative, or vegetative

Include digestion, excretion, cardiac deceleration, near vision

18
Q

approx 75% of all PSNS nerve fibers are where?

A

vagus nerve

19
Q

what are the specific body responses of PSNS?

A

Dilation of skin’s blood vessels
Decreased heart rate, possibly bradycardia
Constriction of bronchi smooth muscle
Contraction of urinary bladder smooth muscle
Contraction of skeletal muscle

20
Q

what are the meds called that turn on the sympaethic nervous system? example? **

A

Sympathomimetic
Adrenergic
Alpha- and beta-adrenergic agonists
Example: epinephrine

21
Q

what are the meds that affect the body as blocking or opposing the SNS (turn off) called? examples?

A

Sympatholytic
Antiadrenergic
Alpha- and beta-adrenergic blocking drugs
Example: clonidine, propranolol

22
Q

what are some meds that stimulate the PSNS? what are they called

A

Parasympathomimetic
Cholinomimetic
Cholinergic
Example: neostigmine

23
Q

what are some meds that block PSNS called? example?

A

Parasympatholytic
Anticholinergic
Cholinergic blocking
Example: atropine