Clinical Bacteriology Flashcards
Staphylococcus aureus causes….
- Inflammatory disease
- Toxin-mediated disease
- MRSA infection
How does Toxic Shock Syndrome (S. aureus) present?
- Fever
- Vomiting
- Rash
- Desquamation
- Shock
- End-organ failure
Staphylococcus epidermidis infects….
prosthetic devices & intravenous catheters
___________ is the 2nd most common cause of uncomplicated UTI in young women.
Staphylococcus saprophyticus
Streptococcus pneumoniae causes….
MOPS
- Meningitis
- Otitis media (children)
- Pneumonia
- Sinusitis
Viridan’s group streptococci causes…
- dental caries (Streptococcus mutans)
- subacute bacterial endocarditis (S. sanguinis)
Streptococcus pyogenes (group A) causes….
-
Pyogenic
- pharyngitis, cellulitis, impetigo
-
Toxigenic
- scarlet fever, toxic shock-like syndrome, necrotizing fasciitis
-
Immunologic
- rheumatic fever, acute glomerulonephritis
J(<3)NES criteria for rheumatic fever
- Joints - polyarthritis
- <3 - carditis
- Nodules (subq)
- Erythema marginatum
- Sydenham chorea
Scarlet fever triad
- Scarlet rash w/ sandpaper-like texture
- Strawberry tongue
- Circumoral pallor
Streptococcus agalactiae (group B) causes….
mainly in babies
- pneumonia
- meningitis
- sepsis
Enterococci (group D) causes…
- UTI
- biliary tract infections
- subacute endocarditis
Streptococcus bovis (group D) causes….
- colonizes the gut
- bacteremia & subacute endocarditis
- colon cancer patients
Symptoms of Corynebacterium diphtheriae
- pseudomembranous pharyngitis (gray-white membrane)
- lymphadenopathy
- myocarditis
- arrhythmias
Corynebacterium diphtheriae pneumonic
ABCDEFG
- ADP-ribosylation
- Beta-prophage
- Corynebacterium
- Diphtheriae
- Elongation Factor 2
- Granules
_________ causes spastic paralysis.
_________causes flaccid paralysis.
Clostridium tetani
Clostridium botulinum
reheated rice syndrome
Bacillus cereus
the only gram (+) organism to produce LPS
Listeria monocytogenes
What kind of TB?
- Ghon focus (mid-zone of lung)
- Fibrocaseous cavity lesion (upper lobes)
- Primary TB
- Secondary TB
What are the 4 classic symptoms of TB?
- Fever
- Night sweats
- Weight loss
- Hemoptysis
What are the 2 forms of Hansen disease?
How do they differ?
-
Lepromatous
- Leonine (lion-like) facies
- Low cell-mediated immunity
- Humoral Th2 response
-
Tuberculoid
- Hypoesthetic, hairless skin plaques
- High cell-mediated immunity
- Th1 type immune response
Haemophilus pneumonic
HaEMOPhilus
- Epiglottitis
- “cherry red” in children
- Meningitis
- Otitis media
- Pneumonia
How do you culture Legionella?
use silver stain –> grow on charcoal yeast extract culture w/ iron & cysteine
Definitions
- Legionnaire’s disease
- Pontiac fever
-
Legionnaire’s disease
- Severe pneumonia
- Fever
- GI & CNS symptoms
-
Pontiac fever
- Mild flu-like syndrome
Pseudomonas pneumonic
PSEUDOmonas
- Pneumonia (CF)
- Sepsis
- External otitis
- UTI
- Drug use
- Diabetic Osteomyelitis
Ecthyma gangrenosum
- rapidly progressive necrotic cutaneous lesions caused by Pseudomonas bacteremia
- immunocompromised patients
E. coli virulence factors
- Fimbriae - cystitis & pyelonephritis
- K capsule - pneumoni, neonatal meningitis
- LPS endotoxin - septic shock