Clinical Bacteriology Flashcards

1
Q

Novobiocin Sensitive

A

S. epidermidis

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2
Q

Novobiocin Resistant

A

S. saprophyticus

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3
Q

Catalase negative and in chains

A

streptococcus

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4
Q

optochin sensitive and bile soluble

A

S. pneumonia

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5
Q

Optochin resistant and bile insoluble

A

Viridans strep like S. Mutans

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6
Q

Bacitracin Sensitive

A

Group A Strep (S. pyogenes)

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7
Q

Bacitracin Resistant

A

Group B Strep (S. agalactiae)

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8
Q

alpha hemolytic bacteria

A

S. pneumonia and Viridans Strep

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9
Q

beta hemolytic bacteria

A

S. aureus, S, pyogenes, S, agalactiae, Listeria

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10
Q

tumbling motility

A

Listeria monocytogenes

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11
Q

2nd most common cause of uncomplicated UTI in young women

A

S. saprophyticus, 1st is E. coli (wipe front to back ladies)

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12
Q

Lancet-shaped, gram positive diplococci

A

S. pneumonia

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13
Q

sepsis in sickle cell anemia and splenectomy

A

S. pneumonia

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14
Q

Most common cause of Meningitis, otitis media in kids, penumonia, and sinusitis

A

MOPS - S. pneumonia

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15
Q

causes dental caries

A

S. Mutans (from Viridans Strep group)

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16
Q

cause SUBacute bacterial endocarditis at damaged valves

A

S. sanguinis (from Viridans Strep group)

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17
Q

Criteria for Rheumatic fever

A
Joints - polyarthritis
O looks like heart - carditis
Nodules - subcutaneous
Erythema mirginatum
Syndenham chorea
S. pyogenes - M protein causes this
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18
Q

rash, sandpaper-like tongue, strawberry tongue, circumoral pallor

A

Scarlet fever from S. pyogenes

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19
Q

Hippurate test positive

A

Group B strep, aka S. agalactiae

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20
Q

When to screen pregnant women for S. agalactiae

A

35-37weeks, if positive tx with intrapartum penicillin prophylaxis

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21
Q

Grow in 6.5% NaCl and bile

A

Entercocci (group D Strep)

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22
Q

Causes subacute endocarditis in colon CA patients

A

Strep Bovis

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23
Q

Elek test for toxin

A

C. diphtheria

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24
Q

Black colonies on Cystine-tellurite agar

A

C. diphtheria

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25
Q

121C for 15minutes

A

to kill spores

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26
Q

Tx for C. difficile

A

metronidazole or oral vancomycin

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27
Q

ulcer with black eschar

A

cutaneous anthrax

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28
Q

woolsorter’s disease

A

pulmonary anthrax - starts as flu and progresses to fever, pulmonary hemorrhage, mediastinitis and shock

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29
Q

reheated rice syndrome

A

bacillus cereus, caused by cereulide

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30
Q

gram positive organism that produces LPS

A

Listeria

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31
Q

Tx of Actinomyces

A

penicillin

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32
Q

Tx of Nocardia

A

sulfonamides

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33
Q

primary TB is localized in what area of lung?

A

mid lung

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34
Q

secondary TB is localized in what area of lung?

A

apical lung

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35
Q

Pott Disease

A

extrapulmonary TB in the vertebrae

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36
Q

interferon-gamma- release assay

A

more specific test of TB, has fewer false positives from BCG vaccination

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37
Q

PPD is negative if:

A

no infection or anergy like taking steroids, malnutritin, immunocompromised and in sarcoidosis

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38
Q

Night sweats, fever, weight loss, hemoptysis

A

Mycobacterium tuberculosis

MAC in AIDS patients

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39
Q

Cord factor

A

in virulent strains of TB that inhibit macrophage maturation and induces the release of TNF-alpha

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40
Q

Reservoir for Leprosy

A

Armadillos

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41
Q

Tuberculoid Leprosy

A

in people with high CMI, largely Th1-response

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42
Q

hypoesthetic hairless plaques on the skin, can’t feel area

A

tuberculoid leprosy

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43
Q

leonine face

A

lepromatous leprosy

44
Q

Lepromatous Leprosy

A

low CMI with humoral Th2 response

45
Q

EMB agar

A

lactose fermenter grow as purple/black colonies

E. coli grows purple with a green sheen

46
Q

What bug ferments maltose?

A

N. Meningitidis

47
Q

N. gonorrhoeae is usually found in what type of cell?

A

neutrophils

48
Q

Causes septic arthritis

A

gonorrhea

49
Q

Tx of gonorrhea

A

Ceftriaxone + (azithromycin or doxycycline for possible chlamydia)

50
Q

prophylaxis for meningitis

A

rifampin

51
Q

BL Adrenal Hemorrhage from N. menigitidis

A

Waterhouse-Friderichsen Syndrome

52
Q

Causes epiglottitis in children

A

H. influenza

53
Q

Tx mucosal infections from Hib with:

A

Amoxicillin +/- Clavulanate

54
Q

Thumbprint sign on lateral neck radiograph

A

H. influenza epiglottitis

55
Q

Patient will have hyponatremia, sever pneumonia, fever, GI and CNS symptoms

A

Legionella pnuemophilia

56
Q

cause of external otitis, swimmer’s ear

A

Pseudomonas aeruginosa

57
Q

ecthyma gangrenosum

A

Pseudomonas aeruginosa

58
Q

K capsule

A

E. coli

59
Q

anemia, thrombocytopenia, and acute renal failure

A

HUS - seen in EHEC and Shigella

60
Q

lobar penumonia in alcoholics and diabetics

A

Klebsiella

61
Q

produce hydrogen sulfide

A

salmonella

62
Q

invades intestinal mucosa and causes a monocytic response

A

salmonella

63
Q

invades intestinal mucosa and cause PMN infiltration

A

Shigella

64
Q

rose spots on abdomen, fever, HA, and diarrhea

A

salmonella typhi

65
Q

organ that salmonella typhi stays dormant in

A

Gallbladder

66
Q

Bloody Diarrhea in kids after poultry, meat and unpasteurized milk

A

Campylobacter jejuni

67
Q

Guillain-Barre and reactive arthritis

A

Campylobacter jejuni

68
Q

Grows at 42C

A

Campylobacter jejuni

69
Q

Can mimic Crohn disease or appendicitis

A

yersinia enterocolitica

70
Q

Tx for H. pylori

A

PPI, clarithromycin + either amoxicillin or metronidazole

71
Q

severe form with jaundice and azotemia from liver and kidney dysfunction - Hawaiian surfers get this

A

Weil Disease from Leptospira interrogans

72
Q

Ixodes tick is a vector for:

A

borrelia burgdorferi and Babesia

also anaplasma

73
Q

Animal urine in water - flu symptoms, jaundice, photophobia with conjunctival suffusion (erythema without exudate)

A

Leptospira interrogans

74
Q

Tx for Lyme’s Disease

A

Doxycycline

75
Q

facial nerve palsy, arthritis, AV nodal block, erythema migrans

A

Lyme disease - Borrelia burgdorferi

76
Q

non-specific syphilis tests

A

VDR/RPR

77
Q

FTA-ABS

A

specific test for syphilis

78
Q

Charcot Joint

A

tertiary syphilis

79
Q

painless chancre

A

primary syphilis

80
Q

maculopapular rash (palms and soles)

A

secondary syphilis

81
Q

aortitis (vasa vasorum destruction)

A

tertiary syphilis

82
Q

constricts with accommodation but is not reactive to light

A

argyll robertson pupil found in tertiary syphilis

83
Q

beef cardiolipin

A

VDRL detects this

84
Q

flu-like syndrome after antibiotics are started - due to killed bacteria releasing pyrogens

A

Jarisch-Herxheimer reaction

85
Q

relapsing fever

A

borrelia recurrentis - transferred by louse

86
Q

puppies, livestock and undercooked meat

A

campylobacter jejuni

87
Q

aerosols of cattle/sheep amniotic fluid

A

Q fever from Coxiella burnetti

88
Q

cellulitis and osteomyelitis from animal bites, cats and dogs

A

pasterella multocda

89
Q

fishy smell and clue cells

A

gardnerella vaginalis

90
Q

Rickettsiae require what?

A

CoA and NAD+

91
Q

rash on hands and feet first and moves inwards - after tick bite

A

rocky mountain spotted fever

92
Q

Endemic typhus

A

from fleas - R. typhi

93
Q

Epidemic typhus

A

human body louse - R. prowazekii

94
Q

rash that starts on trunk and moves out sparing palms and soles

A

Typhus from fleas and louse

95
Q

monocytes with morulae, berry like inclusions

A

Ehrlichiosis

96
Q

granulocytes with morulae

A

anaplasmosis

97
Q

infectious form in chlaydia

A

elementary body

98
Q

Reiter’s Syndrome

A

Reactive arthritis is from Chlamydia

99
Q

cell wall lack muramic acid

A

Chlamydia

100
Q

Blindness in Africa due to follicular conjunctivitis (chronic infection)

A

Chlamydia A, B, C

101
Q

staccato cough in neonatal pneumonia

A

Chlamydia D-K

102
Q

Small, painless ulcers on genitals that later become swollen, painful inguinal LN that ulcerate (buboes)

A

Lymphogranulosum venereum - Chlamydia Types L1, 2, 3

103
Q

Tx of Lymphogranulosum venereum

A

Doxycycline

104
Q

X-ray looks worse than the patient

A

Mycoplasma pneumonia

105
Q

high titer of cold agglutinins (IgM)

A

Mycoplasma pneumonia

106
Q

insidious onset, HA, nonpriductive cough, patchy or diffuse interstitial infiltrate

A

Mycoplasma pneumonia

107
Q

Girls Rule

A

Boys Drool