clinical aspects of RA Flashcards
1
Q
what is the epidemiology of RA ?
A
F3:1M
peak age 40-50, may occur whenever
12-15% in monozygotic twins
2
Q
how is RA investigated ?
A
immunology - anti-CCP, ACPA, rheumatoid factor
radiographs
3
Q
what are symptoms of RA ?
A
pain stiffness immobility poor function systemic symptoms
usually worse in morning, symmetrical
4
Q
what are signs of RA ?
A
swelling
tenderness
limited ROM
redness and heat
5
Q
what are systemic symptoms of RA ?
A
fatigue
weight loss
anaemia
eyes, lungs, nerves, skin, kidneys
6
Q
what scoring system is used to assess RA ?
A
DAS28
<2.4 clinical remission
>5.1 eligibility for biologic therapy
7
Q
what are the outcomes of RA ?
A
50% unable to work
33% out of workplace within 2 years of diagnosis
average 40 days sick leave/ year