Cleft 11/26 Flashcards
1925-1950?
designing a surgical procedure to establish better anatomic result
1960 to present?
emphasis placed on etiology
speech and swallowing function of? general
soft palate
submucous cleft
general
in the muscle
vascular deformaties within this scope
yes
incidence of cleft lip or cleft lip and palata
caucasian 1 in 1,000 births
blacks 1 in 2000
asains 1 in 500 births
incidence in cleft palate only
1 in 2000 births
isolated clefft palate is not ratiall influenced
is cleft palate only racial influenced?
no
incidence of clefting in USA
due to?
1 in 750 births
this is the overall ratio of clefts occurring in the USA
due to mixed gene pool
developing countries incidence
some locations increases to 1 in 350
involves different contaiminents
- environmental and health issues
- needs are greater
relative in family that has a cleft? incidence?
increases
the 750 incidence increases
genetic – incidence of future clefting is evident
palate alone with femal male
2:1
female to male
so female isolated palate
so female to male ratio is very different for the isolated cleft palate patient
incidence with genetics
less than 40% of CL alone or CL/P deformities are genetic origin
less than 20% of isolated CP deformatities are of genetic origin
NUTRIOTION ?
yes – FOLIC ACID DEFICIENCY – neural tube deformaties
food chain contaminatnts
- insecticides – DDT
- defoliants (agent orange)
NUTRIOTION ?
yes – FOLIC ACID DEFICIENCY – neural tube deformaties
food chain contaminatnts
- insecticides – DDT
- defoliants (agent orange)
etiology breakdown
heredity parental age maternal factors nutrition tetragogenic drugs
etiologc maternal factors
hyperemsis – underlying medical problem
threatened abortion- underlying medical problem
measles
stress - endogenous cortisone release
smoking – pregnant women who smoke, and whose fetus carries a particular gene, may be increasing their chances that the baby will be born with a cleft palate
drugs involved in etiology
salicytates
cortisone
barbiturates
dilantin
benzodiazepines
at 8 weeks?
the cleft lip deformaty is complete
cleft lip and alveouls deformity complete at?
cleft palate deformity complete at?
cleft lip and alveolus = 8 weeks
cleft palate deformity = 11 weeks
feeding and airway concerns
general
early on these are big problems