Classic Laboratory Findings Flashcards
Elevated AFP in maternal serum or amniotic fluid
Dating error, NTDs
Anticentromere antibodies
CREST scleroderma
Anti-desmoglein antibodies
Pemphigus vulgaris
Anti-GBM
Goodpasture syndrome (glomerulonephritis and hemoptysis)
Antihistone antibodies
Drug induced lupus (hydralazine, isoniazid, phenytoin, procainamide, associate with slow acetylators)
Anti-IgG antibodies
Rheumatoid arthritis (IgM against IgG is RF)
Antimitochondrial antibodies
Primary biliary cirrhosis
Antineutrophil cytoplasmic antibodies (ANCA)
C anca/PR3-ANCA - Wegners
MPO-ANCA with granulomas - Churg Strauss
MPO-ANCA without granulomas - PSC
ANA, Anti smith, Anti DSDNA
SLE (Type III hypersensitivity)
Antiplatet antibodies
Indiopathic Thrombocytopenic Purpura
Anti-topoisomerase antibodies
Diffuse systemic scleroderma
Anti-TTG, Anti-gliadin, anti-endomysial antibodies
Celiac disease
“Apple core lesions” on barium enema x-ray
Colorectal cancer
Atypical lymphocytes
EBV
Azurophilic peroxidase granular inclusions in granulocytes and myeloblasts
Auer rods (AML)
Bacitracin sensitive
S pyogenes
Bacitracin resistant
S agalactiae
“Bamboo spine”
Ankylosing spondylitis
Basophilic nuclear remnants in RBCs
Howel Jolly Bodies (Asplenia)
Basophilic stippling in RBCs
Lead poisoning or sideroblastic anemia
Bloody or yellow tap on lumbar puncture
Subarachnoid hemorrhage
“Boot shaped” heart
Tetralogy of Fallot
Branching gram + rods with sulfur granule
Actinomyces israelii
Bronchogenic apical lung tumor on imaging
Pancoast tumor (May cause horner syndrome by impinging on cervical sympathetic ganglia)
Brown tumor of bone
Hyperparathyroidism or osteitis fibrosa cystica (hemosidering due to hemorrhage give the brown color)
Cardiomegaly with apical atrophy
Chagas disease
Cellular crescents in bowman capsule
Rapidly progressing glomerularnephritis
“chocolate cyst” in ovary
Endometriosis
Circular grouping of dark tumor cells surrounding pale neurofibrils
Homer wright rosettes (neuroblastoma, medduloblastoma)
Colonies of mucoid pseudomonas in lungs
Cystic fibrosis
Decreased AFP in amniotic fluid
Chromosomal abnormalities
Degeneration of dorsal column fibers
Tabes dorsalis, subacute combined degeneration.
“Delta wave” on EKG, sort PR interval, supraventricular tachycardia
WPW
Depigmentation of neurons in substantia nigra
Parkinsons disease
Desquamated epithelium casts in sputum
Curschmann spirals (bronchiolar asthma), may also be associated with whiled mucous plugs
Disarryed granulosa cells arranged around collections of eosinophilic fluid
Call-Exner bodies (granulosa cell tumor of ovaries)
Dysplastic squamous cervical cells with “rasinoid” nuclei and hyperchromisia
Koilocytes (HPV)
Electrical alternans
Pericardial tamponade
Enlarged cells with intranuclear inclusion bodies
Owl Eye appearance of CMV
Enlarge thyroid cells ith ground-glass nuclei with central clearing
Orphan annie cells (papillary thyroid carcinoma)
Eosinophilic cytoplasmic inclusion in liver cell
Mallory body (alcoholic cirrhosis)
Eosinophilic cytoplsmic inclusion in neuron
Lewy Body (Parkinson and LBD)
Eosinophilic globule in liver
Concilman body (viral hepatitis, yellow fever)
Eosinophilic inclusion bodies in cytoplasm of hippocampal and cerebellar neurons
Negri bodies of rabies
Extracellular amyloid deposition in gray matter of brain
Senile plaques (Alzheimers dementia)