Class 9 Flashcards
amitriptyline Elavil
imipramine Tofranil
CLASS
TCA
amitriptyline Elavil
imipramine Tofranil
ACTION
Decreased reabsorption of norepinephrine and serotonin
amitriptyline Elavil
imipramine Tofranil
USE
Major depressive disorders
Panic disorders
OCD
amitriptyline Elavil
imipramine Tofranil
ADVERSE EFFECTS
Dry mouth Urinary difficulty Constipation Blurred vision Tremors Headache Weight gain Insomnia Photosensitivity Orthostatic hypotension Dysrhythmias w/ cardiac arrest Seizures
amitriptyline Elavil
imipramine Tofranil
Nx IMPLICATIONS/TEACHING
Administer at bedtime
Avoid smoking
Takes 2-4 weeks to achieve effect
Warn of possible orthostatic hypotension
sertraline Zoloft
CLASS
SSRI
sertraline Zoloft
ACTION
Inhibits serotonin reuptake into the presynaptic terminals
sertraline Zoloft
USE
Antidepressant
sertraline Zoloft
ADVERSE EFFECTS
Agitation Anxiousness Overstimulation Insomnia Jitteriness
sertraline Zoloft
Nx IMPLICATION/TEACHING
Do not start within 2 weeks of MAOIs Monitor liver function Monitor seizure disorders Avoid alcohol, OTC, herbs Takes 1-4 weeks
phenelzine Nardil
CLASS
MAOI
sertraline Zoloft
ACTION
Does not breakdown norepinephrine
sertraline Zoloft
USE
Very effective antidepressant
sertraline Zoloft
ADVERSE EFFECTS
AVOID FOODS WITH TYRAMINE Orthostatic hypotension Weight gain Edema Sexual dysfunction