Class 11 Hematologics

Question 1

Plavix clopidogrel

Classification

Answer 1

Antiplatelet

Question 2

Plavix clopidogrel

Primary use

Answer 2

Heart issues

History of clots

Question 3

Plavix clopidogrel

Mechanism of action

Answer 3

Interferes with platelet aggregation

Affects the enzymes ADP and TXA2 given off by the platelets

Question 4

Plavix clopidogrel

Contraindications

Answer 4

Underlying bleeding disorders
Severe liver impairment because liver produces the clotting factors
Active bleeding
Pregnancy

Question 5

Plavix clopidogrel

Drug interactions

Answer 5

Other anticoagulants will intensify
Any acidifying agents with aspirin, carbonic anhydrase inhibitors (Diamox) - diuretic
Antigout medications
NSAIDs

Question 6

Plavix clopidogrel

Adverse effects

Answer 6

Bruising and petechiae
N/V/D and GI pain
Headache dizziness
Watch for platelet number

Question 7

Plavix clopidogrel

Nx Implications/Teaching

Answer 7

Monitor I&O
Watch for bleeding
Discontinue medications 7-10 days prior to surgery
Watch for hearing loss, dizziness, LOC

Question 8

aspirin ASA

classification

Answer 8

Antiplatelet

Question 9

aspirin ASA

Primary use

Answer 9

Heart problems

History of clots

Question 10

aspirin ASA

Mechanism of action

Answer 10

Interferes with platelet aggregation

Affects the enzymes ADP and TXA2 given off by the platelets

Question 11

aspirin ASA

Contraindications

Answer 11

Underlying bleeding disorders
Severe liver impairment because liver produces the clotting factors
Active bleeding
Pregnancy
*Allergic triad: caution with renal, otic disease, or gout

Question 12

aspirin ASA

Drug interactions

Answer 12

Other anticoagulants will intensify
Any acidifying agents with aspirin, carbonic anhydrase inhibitors (Diamox) - diuretic
Antigout medications