Class #22-#23 - Drug designs Flashcards
1
Q
Ibrutinib/Imbruvica treats? How?
A
Chronic Lymphocytic leukemia.
Selective inhibitor of Bruton’s tyrosine kinase (BtK)
2
Q
New drug lowering LDL blood level Pharmacodynamics?
A
Block PCSK9 that cause LDL-receptor in hepatocytes to be broken down.
3
Q
New antihypertensive drugs blocks?
A
Enz. Neprilysin: That breaks down peptides that lower blood pressure and increase Na+ excretion.
4
Q
Anti HCV drug?
A
Sofosbuvir/sovaldi
