CKD Diagnosis and Staging

Question 1

the rate at which a certain event occurs

Answer 1

incidence

Question 2

the total number of cases of a disease in a given population at a given time

Answer 2

Prevalence

Question 3

How do we define CKD?

Answer 3

CKD is kidney damage for > 3 months, with or without decreased GFR as manifested by

1. pathologic abnormalities-
2. Markers of kidney damage
   
   1. blood or urine creatinine levels to measure kidney filtration

OR

1. GFR<60 for more than 3 months with or without kidney damage

Question 4

Stages of CKD

1

2

3

4

5

Answer 4

Stages of Kidney Disease= GFR

1= >90

2 = 60-89

3a = 45-59

3b = 30-44

4 = 15-29

5 = <15

Question 5

what is thet best overall indicies of level of kidney function?

What does this take into account that a normal GFR does not?

Can GFR be estimated with changing S_cr

Answer 5

eGFR (estimation of GFR)

the eGFR takes variables like age, gender, race, body size into account

NO! you can not use a changing serum creatinine to estimate GFR

Question 6

What is the most accurate evaluation for patients with an almost normal GFR?

Answer 6

the CKD-Epi is the most accurate for patients with an almost normal GFR. It is also as accurate for patients with a GFR <60

Question 7

When is a 24 hour urine more accurate than eGFR?

Answer 7

1. Extremes:
   
   1. Age
   2. Weight
   3. Diet
2. Amputated Limbs
3. Determining the need to begin dialysis
4. pregnancy

Question 8

What are normal daily values for:

Total Protein

Albumin

What is the marker of kidney damage?

Answer 8

What are normal daily values for:

Total Protein <150 mg/day

Albumin <30 mg/day

Persistent elevation is the marker of kidney damage