Citalopram Hydrobromide (Antidepressant)

Question 1

What is the brand name of citalopram hydrobromide?

Answer 1

Celexa

Question 2

What strength tablets are available of Celexa?

Answer 2

10 mg, 20 mg, 40 mg

Question 3

What strength oral solution is available for Celexa?

Answer 3

10mg/5mL

Question 4

What is the FTA approved indication and dosage of citalopram hydrobromide?

Answer 4

For the treatment of depression: Begin with a dose of 20 mg given once a day and gradually increased the dose of 40 mg once a day. The full anti-depressant affect may not be seen until four weeks of treatment has passed. At least 14 days should last between the discontinuation of a monoamine oxidase inhibitor and the start of citalopram.

Question 5

Hey what is the mechanism of action of citalopram hydrobromide?

Answer 5

Citalopram blocks in your auto uptake of serotonin, but not of norepinephrine or dopamine, and to human platelets in the CNS.

Question 6

What are the drug interactions of citalopram hydrobromide?

Answer 6

• Coadministration with monoamine oxidase inhibitor’s may produce serious reactions resembling neuroleptic malignant syndrome.
• Potent inhibitors of CYP3A4 have shown to have no effect on the plasma clearance of escitalopram.
• Cimetidine may increase plasma levels.
• Coadministration with aspirin or an inside may lead to the increase risk of upper G.I. bleeding

Question 7

What are the contraindications of citalopram hydrobromide?

Answer 7

• Contraindicated within 14 days of taking monoamine oxidase inhibitor’s.
• Antidepressants increase suicidal thoughts and actions and children, adolescents, and young adults.
• Several reversible cases of hyponatremia have occurred during treatment with citalopram.
• Due to the possibility of suicide attempts, caution should be taken in dispensing large quantities of this medication.
• Use with caution in patients with liver disease and during nursing.
• Abrupt discontinuation of therapy may cause adverse effects including dysphoric mood, your ability, agitation, dizziness, anxiety, confusion, insomnia, and headache.
• Pregnancy Category C

Question 8

What are the adverse effects of citalopram hydrobromide?

Answer 8

Nausea, dry mouth, somnolence, insomnia, diarrhea, ejaculation disorder, and impotence. Other adverse effects occurred at the same rate as placebo

Question 9

What should the RPh tell the patient when counseling them on the use of citalopram hydrobromide?

Answer 9

• May impair cognitive and motor performance. Use caution while operating machinery or when metal alertness is required.
• Up to two weeks maybe needed before therapeutic effects are seen.
• Do not abruptly discontinue medication.
• Avoid alcohol while taking this medication.
• If a dose is missed, skip it and return to normal dosing schedule.
• Pay close attention to any changes, especially sudden changes, and new behaviors, thoughts, or feelings. Antidepressants may increase suicidal thoughts or actions.