CIS Flashcards
1
Q
- What are some causes/differentials for Nausea/Vomiting?
A
- Visceral afferent stimulation
- infections
- mechanical obstruction
- dysmotility
- peritoneal irritation
- hepatobiliary or pancreatic disorders
- topical GI irritants
- postop
- Vestibular disorders
- CNS disorders
- Irritation of chemoreceptor trigger zone
- Chemotherapy
- medications
- systemic disorders
2
Q
- What are the two types of dysphagia?
A
- Oropharyngeal (trouble initiating swallowing)
- Esophageal dysphagia
3
Q
- What can cause oropharyngeal dysphagia?
A
- Neurologic disorders
- Muscular and rheumatologic disorders-Sjogren syndrome
- Metabolic disorders-Cushings
- Structural Disorders-Zenker Diverticulum
- Motility Disorders
4
Q
- Progressive dysphagia with a patient over the age of 50 can be suggestive of _
- When solid foods are worse than liquids _ should be considered
- When there is dysphagia when swallowing both solids and liquids, _ should be considered
A
Esophageal cancer
Mechanical obstruction
Motility Disorder
5
Q
- Etiology of primary alchalasia
- Diagnosis
A
- Impaired relaxation of the LES (loss of NO producing inhibitory neurons in the myenteric plexus)
- Diagnose via barium esophagram
6
Q
- Chaga’s Disease (Secondary Achalasia)
A
- Should be considered in patients from endemic regions (Mexico, Central and South America)
- Caused by parasite =trypanoma cruzi
-
Sx:
- Romana Sign
- Chagoma
7
Q
- What are some chief complaints that would indicate red flags/further workup?
A
- Dysphagia-especially progressive
- Odynophagia
- Hematemesis
- Melena
- Unintentional weight loss
- Persistent vomiting
- Constant/Severe Pain
- Unexplained iron deficiency anemia
- Palpable mass in sternoclavicular fossa
- Lymphadenopathy
- Family history of Upper GI cancer
8
Q
- Signs of a GIB?
A
- Coffee grounds emesis
- Hematemesis
- Melena
- Hematochezia
9
Q
- What bacteria can lead to PUD (Peptic Ulcer Disease?)
A
- H Pylori(specifically Cag-A toxin)
10
Q
- Besides PUD, what can H.Pylori be associated with?
A
- Chronic gastritis (in antrum of stomach)
- Gastric adenocarcinoma
- MALT lymphoma
11
Q
- What two tests are MOST specific for detection of H.Pylori infection?
- What needs to be done before performing these tests?
A
- Urea breath test (used to confirm eradication of H.Pylori)
- Fecal Ag test (used to confirm eradication)
- Patient needs to stop PPi 14 days before each of these tests (so you don’t get a false negative reading)
12
Q
- Gastric Ulcer
- Location:
- Symptom description:
- Treatment:
A
- Location: Lesser curvature/antrum of stomach
- Symptoms:
- Sharp, burning epigastric pain
- Worsens 30 min-1.5 hours after eating
- Treatment:
- PPi
- Eradicate H Pylori
- Stop smoking
13
Q
- Duodenal Ulcer:
- Location:
- Symptoms:
- Treatment:
A
- Location: Anterior wall lining proximal duodenum or distal to 2nd portion of duodenum (ZES)
- Symptoms:
- Gnawing epigastric pain
- Worse 3-5 hours after eating
- May be temporarily relieved by food/eating
- Treatment:
- PPi
- Eradicate H Pylori
- Stop Smoking
14
Q
- Other upper GI ulcers can be caused by:
A
- NSAIDs (inhibit prostaglandins, NO, COX 1 and 2)
- ZES (Zollinger-Ellison)-Gastrinoma
- Cushing ulcer-secondary to intracranial lesion/injury
- Curling ulcer-secondary to severe burns
15
Q
- ZES:
- When to consider
- Tumors are located most commonly in_
- Sometimes associated with _
- Diagnosis
A
- Intractible ulcer/recurrent ulcer disease/severe ulcer disease
- Duodenum (sometimes in pancreas, occasionally in LNs)
- Multiple Endocrine Neoplasia
- Serum Gastrin (>1000)
- Positive Secretin Stimulation Test
- Large mucosal folds on endoscopy