Cirrose Flashcards

1
Q

Cirrose

Função figado

A

Funçao de regular o transito intestinal
NOX, Endotelina
Controle Oxid. nitrico, amonia
Metab. intermediario(carboidratos, lipideos, proteinas)
Sintese proteinas e FC
Metabolisazacao de protoporforina-> bilirrubina Ind-> figado-> bilirrubina D

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2
Q

Cirrose

Estrutura figado

A

Hepatócito
Circulaçao esplancnica-> Porta
Circulaçao esplenica-> Porta

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3
Q

Cirrose

Ciurculaçao intra-hepatica

A

Sinusoides cercados por hepatócitos, banham o figado ate a veia centrolobular
Canaliculo biliar filtra os restos em direçao contraria ao sinusoide

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4
Q

Cirrose

Alteracoes agudas

A
Aumento amonia(encefalopatia)
Hemorragia(FC)
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5
Q

Cirrose

Fisiopato

A

Ageessao cronica-> Célula de ITO produz muito colageno-> Gera tecido fibroso-> Interfere regeneraçao hepatica-> Fibrose

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6
Q

Cirrose

Alteracoes cronicas

A

Reducao FC 7(via extrinseca)
Hiperbilirrubinemia
Aumento globulina
Baixa absorçao de vitaminas lipossolúveis

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7
Q

Cirrose

Nodulos de regeneraçao

A

Nodulos de regeneraçao+ tecido fibroso= cirrose

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8
Q

Cirrose

Diagnostico

A

Biopsia

Elastografia

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9
Q

Cirrose

Compensada x descompensada

A

Compensada 10 anos

Descompensada 1,5 anos

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10
Q

Cirrose

Parametros de avaliaçao

A

Albumina

FC

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11
Q

Cirrose

Escala de

A
BEATA
Bilirrubina
Encefalopatia
Albmina
Temp. protrombina
Ascite
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12
Q

Cirrose

Escala de meld

A

Caneta BIC
Bilirrubina
INR
Creatinina

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13
Q

Cirrose

Síndrome Hepatorrenal

A

qq

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14
Q

Cirrose causas

Hepatie alcoolica

A

AST+ e ALT-
Febre
Ictericia

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